Deaths of children aged under 5 years and related factors in the Islamic Republic of Iran: a populationbased case-control study.

The study was conducted to determine the family, social and economic factors associated with deaths of children aged under 5 years. A registry-based nested case-control study was conducted of the deaths of all children aged under 5 years in Kohgilooyeh and Boyer-Ahmad Province in the Islamic Republic of Iran. For each death, two controls were randomly selected among children of the same age, sex and place of residence (186 cases and 372 controls). Congenital abnormality (37.6%) and preterm birth (29.0%) were the two most frequent causes of death among children aged under 5 years. No vaccine-preventable disease was reported as the cause of death. The strongest associations were found with consanguinity of the parents (OR = 3.92; 95% CI = 2.27-6.85 for being first cousins in comparison with no family relation; P < 0.001) and with domestic violence to the mother during pregnancy (OR = 3.13; 95% CI = 1.60-6.17; P < 0.01). The main causes of death of children aged under 5 years in the Province were congenital abnormality and prematurity.

Deaths of children aged under 5 years and related factors in the Islamic Republic of Iran: a population-based case-control study

The study was conducted to determine the family, social and economic factors associated with deaths of children aged under 5 years. A registry-based nested case-control study was conducted of the deaths of all children aged under 5 years in Kohgilooyeh and Boyer-Ahmad Province in the Islamic Republic of Iran. For each death, two controls were randomly selected among children of the same age, sex and place of residence [186 cases and 372 controls]. Congenital abnormality [37.6%] and preterm birth [29.0%] were the two most frequent causes of death among children aged under 5 years. No vaccine-preventable disease was reported as the cause of death. The strongest associations were found with consanguinity of the parents [OR = 3.92; 95% CI = 2.27-6.85 for being first cousins in comparison with no family relation; P < 0.001] and with domestic violence to the mother during pregnancy [OR = 3.13; 95% CI = 1.60-6.17; P < 0.01]. The main causes of death of children aged under 5 years in the Province were congenital abnormality and prematurity

La présente étude a été menée pour déterminer les facteurs familiaux, sociaux et économiques associés aux décès des enfants de moins de cinq ans. Une étude cas-témoin nichée reposant sur les données de registres a été menée sur les décès de tous les enfants de moins de cinq ans dans la province de Kohgilooyeh et Boyer-Ahmad en République islamique d'Iran. Pour chaque décès, deux témoins étaient sélectionnés de façon aléatoire parmi les enfants du même âge, sexe et lieu de résidence [186 cas et 872 témoins]. Les malformations congénitales?[37,6%] et les naissances prématurées [29,0%] constituaient les deux causes de décès les plus fréquentes parmi les enfants de moins de cinq ans. Aucune maladie à prévention vaccinale n'a été rapportée comme cause de décès. Les associations les plus fortes étaient liées à la consanguinité des parents [OR = 3,92 ; IC à 95% = 2,27-6,85 pour les cousins de premier degré en comparaison avec les sujets n'ayant aucun lien de parenté ; p < 0,001] et à la violence conjugale envers les mères pendant la grossesse [OR = 3,13 ; IC à 95% = 1,60-6,17 ; p < 0,01]. Les principales causes de décès des enfants de moins de cinq ans dans la province étaient les malformations congénitales et la prématurité