[Macrokinetics of vital manifestations in microbes].

An equation for the complete dynamics of the growth and die-off indices of microbes has been obtained in the framework of the macrokinetic approach. The equation allows differentiation of intervals with different values of kinetic characteristics. Analytical expressions were found for coefficients of the model and interval boundaries with the kinetics of growth and die-off of microbes. The adequacy of the equation was confirmed in the cases of experimental dynamics: the growth of Candida albicans culture in a Sabouraud liquid medium, the number of viable cells of Brochothrix thermosphacta in meat extract, and trimethylbutanol secretion by these organisms.

[The 1st results in the realization of the Harm Reduction program for intravenous narcotic users in the city of Penza]. / Pervye rezul'taty realizatsii programmy "Snizhenie vreda" dlia potrebitelei vnutrivennykh narkotikov g. Penza.

To achieve the aims of the project, the following stages were consecutively defined: (1) the exchange of syringes, organized by outreach workers, with the simultaneous popularization of the project, (2) the orientation of intravenous drug users to attending syringe exchange stations and (3) the extension of the area covered by the activities of outreach workers. Our experience showed that outreach workers, especially those working in the street, were the main force to count on for achieving success in the work of the projects. The budget of the project should provide for the publication of information material. Special assignments for outreach workers to study some concrete problem (drug service, the use of blood, etc.) can be useful. It is expedient to raise the status of syringe exchange stations by turning them into multi-purpose consultation centers.