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Vopr Onkol ; 28(7): 28-34, 1982.
Article in Russian | MEDLINE | ID: mdl-7101824

ABSTRACT

The results of the treatment of 75 patients with ovarian carcinoma of epithelial origin are reported. The authors give a randomised clinical comparison of the efficacy of two schemes of complex treatment of 54 patients with ascitic ovarian carcinoma and 21 patients with non-ascitic ovarian carcinoma. The first scheme included cytoxan chemotherapy plus surgery plus polychemotherapy (25 patients); the second--surgery plus polychemotherapy (29 patients). Patients with non-ascitic carcinoma (21) received the second type of treatment. Polychemotherapy consisted of two alternating schedules: 5 fluorouracil plus cyclophosphamide and hexamethylamine plus cyclophosphamide after a two week interval. Better results were obtained in the group of patients treated surgically at the initial stage of treatment.


Subject(s)
Ovarian Neoplasms/therapy , Castration , Drug Therapy, Combination , Female , Humans , Neoplasm Staging , Ovarian Neoplasms/mortality , Ovarian Neoplasms/pathology , Postoperative Care/methods , Prognosis , Time Factors
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