ABSTRACT
Two black male siblings with pseudohypoaldosteronism are reported. They became ill in infancy with failure to thrive, renal salt wasting, and marked elevation of plasma aldosterone. These two patients illustrate many features of this uncommon disorder, as well as a severe metabolic acidosis. To our knowledge, this is the first report of pseudohypoaldosteronism in a black family.
Subject(s)
Acidosis, Renal Tubular/diagnosis , Aldosterone/metabolism , Acidosis, Renal Tubular/diet therapy , Acidosis, Renal Tubular/physiopathology , Humans , Infant , Infant, Newborn , Male , Sodium/administration & dosageABSTRACT
Mucocutaneous lymph node syndrome (MLNS) is being more frequently reported in the United States, and it appears to be an important disease of childhood. Fifteen infants and children with MLNS were treated at the Louisiana State University teaching hospitals in Shreveport and Monroe between August 1978 and January 1981. A cluster of nine of the cases (60%) occurred between February and May 1980. In this series the male to female ratio was 2:1, and 53% of the patients were between 11 and 15 months of age. In five of the patients, platelet counts and erythrocyte sedimentation rates were monitored for at least four weeks.
