ABSTRACT
Serum triiodothyronine (T3) and thyroxine (T4) concentrations were determined after IV administration of 200 micrograms of thyrotropin-releasing hormone (TRH) to 10 healthy euthyroid dogs. Significant (P less than 0.05) changes were not found in the T3 concentration throughout an 8-hour sampling interval. All dogs had a significant increase (P less than 0.05) in the T4 concentration at 4, 5, 6, 7, and 8 hours after TRH administration. The largest increase in the serum T4 concentration occurred 4 hours after TRH injection. From 4 to 8 hours after TRH administration, the mean increase above basal T4 concentrations was 13.9 +/- 5.4 ng/ml.
Subject(s)
Dogs/physiology , Thyroid Function Tests/veterinary , Thyroid Gland/physiology , Thyrotropin-Releasing Hormone , Thyroxine/blood , Triiodothyronine/blood , Animals , Female , Male , Radioimmunoassay/veterinary , Thyroid Function Tests/methods , ThyrotropinABSTRACT
One oral dose of ivermectin successfully rid a dog of Capillaria aerophila that were infecting the nasal passages. Diagnosis was made by finding the eggs in the feces and in the nasal discharge, and or finding the worms in a biopsy specimen taken from the nasal passage. Ivermectin was chosen because of ease of administration, expected efficacy, and minimal expense. Although this dog did not show any of the adverse CNS effects associated with the use of ivermectin, these potential side-effects should be kept in mind any time this anthelmintic is used in dogs.