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Biofizika ; 52(3): 452-9, 2007.
Article in Russian | MEDLINE | ID: mdl-17633533

ABSTRACT

The binding of Gd3+ ions to linear double-stranded DNA molecules in water-salt solutions or in liquid-crystalline dispersions is accompanied by sharp changes in their optical and X-ray characteristics. Depending on the initial conditions of complex formation, the binding of Gd3+ ions either to DNA bases or phosphate groups occurs, which leads to changes in the properties of the liquid-crystalline dispersions. The packing of neighboring DNA molecules in particles of the liquid-crystalline dispersion of the complex DNA-Gd3+ depends strongly on the concentration of Gd3+ ions. This process is accompanied by a decrease in the amplitude of Bragg's reflection maximum. The unique properties of the developed material open the possibilities for its practical use.


Subject(s)
DNA/chemistry , Gadolinium/chemistry , Liquid Crystals/chemistry , Crystallography, X-Ray , Nucleic Acid Conformation , Solutions/chemistry
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