1.
Microbios
; 86(348): 163-74, 1996.
Article
in English
| MEDLINE
| ID: mdl-8885416
ABSTRACT
Hyperexpression of the enzyme, parahydroxyphenylpyruvate dioxygenase (pHPPH; melA), in the tyrosine degradative pathway yields excess homogentisic acid which oxidatively polymerizes to pyomelanin. Depression of melA in Shewanella colwelliana strain D was found to result from a single base pair transition upstream of the promoter. This was the sole lesion detected in pHPPH hyperexpressing strains. It is suggested that a T to C transition alters the mRNA structure, exposing the ribosome binding site, thereby enhancing translational efficiency.
Subject(s)
4-Hydroxyphenylpyruvate Dioxygenase/genetics , DNA, Bacterial , Gram-Negative Facultatively Anaerobic Rods/enzymology , 4-Hydroxyphenylpyruvate Dioxygenase/metabolism , Base Sequence , Molecular Sequence Data , Nucleic Acid Conformation , Promoter Regions, Genetic , RNA, Bacterial
2.
Phys Rev B Condens Matter
; 52(4): 2395-2402, 1995 Jul 15.
Article
in English
| MEDLINE
| ID: mdl-9981305
3.
Phys Rev B Condens Matter
; 49(19): 13335-13341, 1994 May 15.
Article
in English
| MEDLINE
| ID: mdl-10010266
4.
Phys Rev B Condens Matter
; 48(1): 562-568, 1993 Jul 01.
Article
in English
| MEDLINE
| ID: mdl-10006809