1.
Lupus
; 20(14): 1547-50, 2011 Dec.
Article
in English
| MEDLINE
| ID: mdl-21993386
ABSTRACT
Pure red cell aplasia (PRCA) is a recognized but rare complication of systemic lupus erythematosus (SLE) and is characterized by the near absence of red blood cell precursors in the bone marrow but with normal megakaryocyte and granulocytes. We report a novel case of acquired PRCA occurring simultaneously with immune thrombocytopenia in the context of active SLE. Both syndromes were refractory to conventional treatment but responded to rituximab and cyclophosphamide.
Subject(s)
Lupus Erythematosus, Systemic/complications , Red-Cell Aplasia, Pure/etiology , Thrombocytopenia/immunology , Antibodies, Monoclonal, Murine-Derived/therapeutic use , Antirheumatic Agents/therapeutic use , Cyclophosphamide/therapeutic use , Female , Glucocorticoids/therapeutic use , Humans , Lupus Erythematosus, Systemic/drug therapy , Red-Cell Aplasia, Pure/drug therapy , Rituximab , Thrombocytopenia/drug therapy , Young Adult
2.
BMJ
; 321(7267): 1019-20, 2000 Oct 21.
Article
in English
| MEDLINE
| ID: mdl-11203209