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1.
Allergol. immunopatol ; 43(5): 461-468, sept.-oct. 2015. tab, graf
Article in English | IBECS | ID: ibc-141106

ABSTRACT

BACKGROUND: Migrants from developing to Western countries tend to become more sensitised to host than to origin country allergens, although substantial changes in migration patterns have occurred in recent decades. Methods We investigated adult immigrants with respiratory allergy, first tested for allergic sensitisation between 1985 and 2012 in a highly industrialised area in Italy. A comparison was made of the sensitisation pattern between immigrants and a random sample of native-born subjects affected by a respiratory allergy, and among immigrants according to macro-region of origin and time period. RESULTS: Between 1985 and 2012, 480 immigrants with respiratory allergy had a first positive allergy test. Immigrants were sensitised mainly to grass (67.1%), house dust mites (HDM) (38.5%) and birch (27.5%), with a pattern of sensitisation very similar to that observed in Italians (native-born). An increase in the proportion of subjects with asthma and of subjects with polysensitisation was observed from the first (1985-2002) to the middle (2003-2007) and the most recent period (2008-2012). In recent years, the proportion of subjects with polysensitisation in immigrants is higher than in Italians (native-born) (53.3% vs. 40.1%). Among immigrants, the risk of sensitisation to grass was higher in those from Sub-Saharan Africa (odds ratio, OR = 2.76) and Latin America (OR = 2.49), whereas risk of sensitisation to HDM was higher among immigrants from South Asia (OR = 2.71), compared to immigrants from Eastern Europe. CONCLUSIONS: Immigrants develop multiple sensitisations more frequently than native-born people, and are especially sensitised to local allergens; the country of origin seems to play a role


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Subject(s)
Adult , Female , Humans , Male , Transients and Migrants , Asthma/epidemiology , Rhinitis/epidemiology , Respiratory Hypersensitivity/epidemiology , Pyroglyphidae , Betula , Cynodon , Pollen , Allergens , Epidemiological Monitoring/trends , Hypersensitivity, Immediate/epidemiology , Hypersensitivity/epidemiology , Industrial Zones , Italy/epidemiology
2.
Allergol Immunopathol (Madr) ; 43(5): 461-8, 2015.
Article in English | MEDLINE | ID: mdl-25456530

ABSTRACT

BACKGROUND: Migrants from developing to Western countries tend to become more sensitised to host than to origin country allergens, although substantial changes in migration patterns have occurred in recent decades. METHODS: We investigated adult immigrants with respiratory allergy, first tested for allergic sensitisation between 1985 and 2012 in a highly industrialised area in Italy. A comparison was made of the sensitisation pattern between immigrants and a random sample of native-born subjects affected by a respiratory allergy, and among immigrants according to macro-region of origin and time period. RESULTS: Between 1985 and 2012, 480 immigrants with respiratory allergy had a first positive allergy test. Immigrants were sensitised mainly to grass (67.1%), house dust mites (HDM) (38.5%) and birch (27.5%), with a pattern of sensitisation very similar to that observed in Italians (native-born). An increase in the proportion of subjects with asthma and of subjects with polysensitisation was observed from the first (1985-2002) to the middle (2003-2007) and the most recent period (2008-2012). In recent years, the proportion of subjects with polysensitisation in immigrants is higher than in Italians (native-born) (53.3% vs. 40.1%). Among immigrants, the risk of sensitisation to grass was higher in those from Sub-Saharan Africa (odds ratio, OR=2.76) and Latin America (OR=2.49), whereas risk of sensitisation to HDM was higher among immigrants from South Asia (OR=2.71), compared to immigrants from Eastern Europe. CONCLUSIONS: Immigrants develop multiple sensitisations more frequently than native-born people, and are especially sensitised to local allergens; the country of origin seems to play a role.


Subject(s)
Emigrants and Immigrants , Respiratory Hypersensitivity/ethnology , Urban Health/ethnology , Adult , Africa South of the Sahara/ethnology , Asia/ethnology , Developed Countries , Developing Countries , Europe, Eastern/ethnology , Female , Humans , Industrial Development , Italy/epidemiology , Latin America/ethnology , Male , Respiratory Hypersensitivity/diagnosis , Respiratory Hypersensitivity/immunology , Urban Health/statistics & numerical data
3.
Int J Immunopathol Pharmacol ; 26(3): 801-6, 2013.
Article in English | MEDLINE | ID: mdl-24067481

ABSTRACT

Buckwheat allergy is considered a rare food allergy outside of Asia. In Europe, buckwheat has been described mainly as a hidden allergen. Data on the prevalence of buckwheat hypersensitivity in non-Asian countries is very poor. The aim of this multicenter study was to evaluate the prevalence of buckwheat sensitization and its association with other sensitizations among patients referred to allergy clinics in different geographic areas of Italy. All patients referred to 18 Italian allergy clinics from February through April 2011 were included in the study and evaluated for sensitization to buckwheat and other allergens depending on their clinical history. A total of 1,954 patients were included in the study and 61.3 percent of them were atopic. Mean prevalence of buckwheat sensitization was 3.6 percent with significant difference between Northern (4.5 percent), Central (2.2 percent) and Southern (2.8 percent) regions. This is, to our knowledge, the largest epidemiological survey on buckwheat allergy reported outside of Asia. Buckwheat is an emerging allergen in Italy, being more frequently associated to sensitization in Northern regions.


Subject(s)
Allergens , Fagopyrum/adverse effects , Food Hypersensitivity/epidemiology , Adult , Female , Food Hypersensitivity/diagnosis , Food Hypersensitivity/immunology , Humans , Italy/epidemiology , Male , Middle Aged , Predictive Value of Tests , Prevalence , Referral and Consultation , Skin Tests , Young Adult
4.
J Org Chem ; 71(13): 4943-50, 2006 Jun 23.
Article in English | MEDLINE | ID: mdl-16776525

ABSTRACT

Three different bile acid-derived biphenyl phosphites were synthesized, starting from cholic and deoxycholic acids and biphenol, and their stereochemical features were checked by CD and NMR spectroscopies. On the basis of the spectroscopic results, the capability of the cholestanic system to induce a prevalent sense of twist on the biphenyl moiety of the bile acid-derived phosphites as well as their tropos nature was inferred.

6.
Chir Ital ; 48(4): 13-9, 1996.
Article in Italian | MEDLINE | ID: mdl-9522094

ABSTRACT

The authors describe their experience in the treatment of dumbbell neurogenic tumours, intrathoracic and intraspinal, with particular reference to clinical presentation, diagnostic for imaging, anatomo-pathological classification and surgical treatment, comparing their clinical cases (9) with the international literature, accurately reviewed. The authors think that the best surgical treatment is the combined approach, in only one stage, of thoracic surgeon and neurosurgeon by hemilaminectomy and extended costotrasversectomy, reserving hemilaminectomy and thoracotomy only for the tumours with big dimension of intrathoracic portion.


Subject(s)
Ganglioneuroma/surgery , Neurilemmoma/surgery , Neurofibroma/surgery , Spinal Neoplasms/surgery , Thoracic Neoplasms/surgery , Adult , Aged , Aged, 80 and over , Female , Ganglioneuroma/diagnosis , Ganglioneuroma/pathology , Humans , Laminectomy , Magnetic Resonance Imaging , Male , Middle Aged , Neoplasm Invasiveness , Neurilemmoma/diagnosis , Neurilemmoma/pathology , Neurofibroma/diagnosis , Neurofibroma/pathology , Radiography, Thoracic , Spinal Neoplasms/diagnosis , Spinal Neoplasms/pathology , Thoracic Neoplasms/diagnosis , Thoracic Neoplasms/pathology , Thoracotomy , Tomography, X-Ray Computed
7.
Ecotoxicol Environ Saf ; 28(1): 1-13, 1994 Jun.
Article in English | MEDLINE | ID: mdl-7523063

ABSTRACT

Human milk from four major Italian cities was analyzed for individual congeners of polychlorinated biphenyls (PCB), DDT, DDE, hexachlorobenzene, and beta-hexachlorocyclohexane. Minimum and maximum concentrations in milk from individual mothers for most compounds ranged between one order of magnitude below and above the mean value of all mothers. Good agreements were found between results from pooled samples and mean values of individual samples. No statistically significant difference between cities was found and the levels in milk from Italian mothers did not differ significantly from published levels from other parts of the world. Principal component analyses revealed that the PCB congener distribution pattern was very similar in all mothers, independent of location. Average concentrations in milk from the four cities were 19(+/- 5) micrograms liter-1 total PCB or 3.2(+/- 0.8) ng liter-1 toxicity equivalents according to the most conservative TCDD toxicity equivalent factors of PCBs proposed in the literature, 70(+/- 18) micrograms liter-1 DDE, 4.5(+/- 1.2) micrograms liter-1 DDT, 5.6(+/- 1.9) micrograms liter-1 HCB, and 4.4(+/- 1.7) micrograms liter-1 beta-hexachlorocyclohexane.


Subject(s)
Insecticides/analysis , Milk, Human/chemistry , Polychlorinated Biphenyls/analysis , Female , Humans , Italy , Maximum Allowable Concentration
9.
Chir Ital ; 44(3-4): 167-73, 1992.
Article in Italian | MEDLINE | ID: mdl-1306141

ABSTRACT

Obturator hernia, which is a rare cause of intestinal occlusion, generally presents non-specific signs and symptoms. Radiology may be sometimes useful for the diagnosis. Four cases of obturator hernia are described, and the possible surgical access routes are illustrated, emphasizing the use of prosthetic mesh.


Subject(s)
Hernia, Obturator/surgery , Aged , Aged, 80 and over , Emergencies , Female , Hernia, Obturator/complications , Humans , Ileal Diseases/etiology , Ileal Diseases/surgery , Intestinal Obstruction/etiology , Intestinal Obstruction/surgery , Jejunal Diseases/etiology , Jejunal Diseases/surgery , Middle Aged , Sigmoid Diseases/etiology , Sigmoid Diseases/surgery
10.
Chir Ital ; 44(3-4): 174-9, 1992.
Article in Italian | MEDLINE | ID: mdl-1306142

ABSTRACT

A splenic arteriovenous fistula is a situation often presenting with signs of portal hypertension and with a characteristic murmur. Though rare, the possibility of a splenic arteriovenous fistula must be borne in mind in differential diagnosis, since it can be corrected surgically by resolving the portal hypertension.


Subject(s)
Arteriovenous Fistula/surgery , Splenic Artery/surgery , Splenic Vein/surgery , Adult , Arteriovenous Fistula/complications , Arteriovenous Fistula/diagnosis , Ascites/diagnosis , Ascites/etiology , Ascites/surgery , Diagnosis, Differential , Female , Humans , Hypertension, Portal/diagnosis , Hypertension, Portal/etiology , Hypertension, Portal/surgery , Radiography , Splenic Artery/diagnostic imaging , Splenic Vein/diagnostic imaging
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