ABSTRACT
Thirty patients aged 45-62 years (mean 54.8 +/- 3.7) have been studied. Pronoran (piribedil) was used for treatment of age-related memory impairment in dosage 50 mg per day during 30 and 90 days (2 groups of 15 patients). Psychophysiological examination included a study of sensomotor activity (time for visual-motor reactions--simple and complex) and functional lability of visual analyzer as well as evaluation of cognitive processes--memory and attention. Patients were examined before and after therapy of different duration. Pronoran exerted a positive effect on psychophysiological state of elderly people, improving memory and attention and increasing the velocity of psychomotor reactions and lability of nervous processes. The longer was the therapy, the more improved were above traits. Along with cogniotropic and mnemotoric (an influence on operative memory) effects of pronoran, its non-specific activating impact is described.
Subject(s)
Dopamine Agonists/therapeutic use , Memory Disorders/drug therapy , Piribedil/therapeutic use , Age Factors , Analysis of Variance , Dopamine Agonists/administration & dosage , Dopamine Agonists/pharmacology , Female , Humans , Male , Memory/drug effects , Memory Disorders/diagnosis , Memory, Short-Term/drug effects , Middle Aged , Neuropsychological Tests , Piribedil/administration & dosage , Piribedil/pharmacology , Time Factors , Treatment OutcomeABSTRACT
The paper deals with two aspects of psychophysiological examination made within the psychophysiological evaluation of the condition of healthy persons as well as within the psychophisiological express-diagnosis of latent and initial stress reactions. The level of psychophysiological indices ensuring the integrated functioning of the CNS was evaluated by the KPFK-99 "Psyhomat" automated set designed for psychophysiological diagnosis of man. Besides, its regulatory components were evaluated by means of the "VNS-spectrum" equipment: VNS parameters were analyzed (rhythmological evaluation of the vegetative tonus, vegetative reactivity and vegetative support). The psychological status was examined by a set of psychodiagnostic and psychosocial tests.
Subject(s)
Brain/physiology , Diagnosis, Computer-Assisted/methods , Stress, Psychological/diagnosis , Adolescent , Adult , Diagnosis, Computer-Assisted/instrumentation , Health Status , Humans , Male , Middle Aged , Neuropsychological Tests , PsychophysiologyABSTRACT
The paper presents a complex psychophysiological analysis of the effect of a combined administration of pantogam and potassium orotate (kalii orotas) on the dynamics of cognitive function in patients with neurotic disorders. The investigation was conducted in an 8-stage consecutive cycle and employed computer-aided diagnostic system. It was established that the combined use of pantogam and potassium orotate produces a positive effect upon the dynamics of restoration of the attention and memory mechanisms in neurotic patients.
Subject(s)
Attention/drug effects , Memory/drug effects , Neurotic Disorders/drug therapy , Nootropic Agents/therapeutic use , Orotic Acid/therapeutic use , Pantothenic Acid/therapeutic use , gamma-Aminobutyric Acid/therapeutic use , Drug Therapy, Combination , Humans , Neurotic Disorders/psychology , Pantothenic Acid/analogs & derivatives , gamma-Aminobutyric Acid/analogs & derivativesABSTRACT
The paper deals with psychophysiological monitoring on an automatic [symbol: see text] phi K-01 psychophysiological diagnosis unit made in Russia. The unit is intended to detect latent and initial manifestations of stress reactions in healthy individuals and to evaluate the efficiency of psychopharmacological therapy and psychotherapy.
