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Ukr Biokhim Zh (1978) ; 65(2): 107-11, 1993.
Article in Russian | MEDLINE | ID: mdl-8236523

ABSTRACT

The influence of chlorophos on the endoplasmatic reticulum of rat liver has been studied using the methods of gas-liquid chromatography and fluorescence. Experiments have demonstrated an increase of lysophosphatidylethanolamine, total phospholipids, unsaturated fatty acids (C20:4 n6, C18:1 n11, C18:1 n7) and a decrease of phosphatidylserine and phosphatidylethanolamine. Changes in microviscosity and surface charge were also shown.


Subject(s)
Endoplasmic Reticulum/drug effects , Lipid Metabolism , Microsomes, Liver/drug effects , Trichlorfon/poisoning , Animals , Fatty Acids/metabolism , Lysophospholipids/metabolism , Male , Phosphatidylethanolamines/metabolism , Phosphatidylserines/metabolism , Phospholipids/metabolism , Rats , Viscosity
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