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Food Chem Toxicol ; 56: 483-90, 2013 Jun.
Article in English | MEDLINE | ID: mdl-23376780

ABSTRACT

This study presents a consumer and farmer safety evaluation on the use of four botanical pesticides in pepper berry crop protection. The pesticides evaluated include preparations from clove, tuba root, sweet flag and pyrethrum. Their safety evaluation was based on their active ingredients being eugenol, rotenone, ß-asarone and pyrethrins, respectively. Botanical pesticides from Acorus calamus are of possible concern because of the genotoxic and carcinogenic ingredient ß-asarone although estimated margins of exposure (MOE) for consumers indicate a low priority for risk management. For the other three botanical pesticides the margin of safety (MOS) between established acute reference doses and/or acceptable daily intake values and intake estimates for the consumer, resulting from their use as a botanical pesticide are not of safety concern, with the exception for levels of rotenone upon use of tuba root extracts on stored berries. Used levels of clove and pyrethrum as botanical pesticides in pepper berry crop production is not of safety concern for consumers or farmers, whereas for use of tuba root and sweet flag some risk factors were defined requiring further evaluation and/or risk management. It seems prudent to look for alternatives for use of sweet flag extracts containing ß-asarone.


Subject(s)
Consumer Product Safety , Crops, Agricultural , Environmental Exposure/analysis , Pest Control, Biological/methods , Pesticides/pharmacology , Piper nigrum , Acorus/chemistry , Allylbenzene Derivatives , Anisoles/toxicity , Chrysanthemum cinerariifolium/chemistry , Derris/chemistry , Eugenol/toxicity , Evaluation Studies as Topic , Humans , Plant Roots/chemistry , Pyrethrins/toxicity , Risk Assessment , Rotenone/toxicity , Syzygium/chemistry
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