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1.
Prog Urol ; 32(12): 862-867, 2022 Oct.
Article in French | MEDLINE | ID: mdl-35623942

ABSTRACT

OBJECTIVES: The objective of this study was to evaluate the sexuality of SS sickle cell patients with a history of priapism. METHODS: This was a case-control study of adult SS sickle cell patients. The occurrence of priapism as well as the nature of the priapism had been investigated. The patients were subdivided into three groups: Group 1 (no priapism), Group 2 (intermittent priapism) and Group 3 (acute priapism). The patients' sexuality was studied using the IIEF-15 questionnaire. RESULTS: We interviewed 191 SS sickle cell patients. The mean age was 27.1±7.1 years. Priapism was observed in 43.5 %. Only 77 patients were eligible for the IIEF15 questionnaire. Groups 1 and 2 performed significantly better than group 3 on erectile function (EF) and orgasmic function (OF) scores. There was no significant difference in the EF and OF scores between groups 1 and 2. No significant difference was observed between the three groups for the scores of sexual desire (SD), intercourse satisfaction (IS), and overall satisfaction (OS). The impairment of erectile function in group 2 was related to the age of the first episode of priapism and the last episode. The impairment of erectile function in group 3 was related to the duration of evolution (P<0.05). CONCLUSION: This study shows that priapism is responsible for impaired erectile function in SS adult sickle cell patients. A program to prevent intermittent episodes of priapism should be put in place.


Subject(s)
Anemia, Sickle Cell , Erectile Dysfunction , Priapism , Adult , Anemia, Sickle Cell/complications , Anemia, Sickle Cell/epidemiology , Case-Control Studies , Erectile Dysfunction/epidemiology , Humans , Male , Priapism/etiology , Senegal , Sexuality , Young Adult
2.
Ann Cardiol Angeiol (Paris) ; 68(2): 115-119, 2019 Apr.
Article in French | MEDLINE | ID: mdl-30314668

ABSTRACT

INTRODUCTION: Acute coronary syndromes have been rarely studied in the female population in Sub-Saharan Africa. This Sub-Saharan serie has shown an increase in the prevalence of acute coronary syndromes among the female population, compared to previous studies. Through this retrospective study, we evaluated the epidemiological, clinical, paraclinical, therapeutic and evolutionary features of acute coronary syndromes on women at the Principal Hospital of Dakar. METHODOLOGY: This was a retrospective study of patients hospitalized for acute coronary syndrome over a period of 5 years from January 1st, 2010 to December 31st, 2014, at the Cardiology Department of the Principal Hospital of Dakar. RESULTS: The prevalence of diabetes and obesity was statistically higher for women than for men. Atypical symptomatology was much more apparent (P=0.0000), admission times at the emergency department for acute coronary syndromes were relatively longer (=0.005). Therapeutically, medical care was almost identical regardless of gender. CONCLUSION: In Senegal, acute coronary syndrome in women is characterized by the atypical symptomatology with delayed diagnosis and management. The fight against this reputedly masculine pathology requires a good awareness campaign.


Subject(s)
Acute Coronary Syndrome , Acute Coronary Syndrome/diagnosis , Acute Coronary Syndrome/drug therapy , Acute Coronary Syndrome/epidemiology , Africa South of the Sahara , Aged , Anticoagulants/therapeutic use , Cardiology Service, Hospital , Diabetes Mellitus/epidemiology , Female , Humans , Male , Obesity/epidemiology , Prevalence , Retrospective Studies , Senegal/epidemiology , Sex Distribution , Sex Factors , Symptom Assessment , Thrombolytic Therapy/statistics & numerical data , Time-to-Treatment/statistics & numerical data
3.
Prog Urol ; 28(7): 377-381, 2018 Jun.
Article in French | MEDLINE | ID: mdl-29627339

ABSTRACT

OBJECTIVE: To report our experience with anastomotic uretroplasty (AU) due to male urethral stricture disease (USD) and to identify factors affecting the results. PATIENTS AND METHODS: We conducted a retrospective study over a period of 4 years and 6 months (July 2012 to December 2016). Any subsequent use of endoscopic urethrotomy or new urethroplasty was considered a failure. RESULTS: Forty-eight cases were included. The mean age of patients was 53.5±17.3 years (23-87 years). Urinary retention was the reason for consultation in 42 cases (87.5%). The most common localization of USD was the bulbar urethra (n=45). The mean length of USD was 1.23±0.62cm (0.5-3cm) with a median length of 1cm. The etiology was post-infectious in 56.3% of cases. More than half (58.3%) of patients had already undergone at least one urethral manipulation. After an average follow-up of 21.1±12.6 months (1 to 52 months), the overall success rate was 77.1%. In univariate analysis, length, cause and location of the stricture, age of patient, the presenting symptoms of the stricture, previous urethral manipulation and surgeon experience did not significantly impact on the success rate of anastomotic urethroplasty at one and two years follow-up. CONCLUSION: The AU had provided good results in our practice. The infectious origin of the stricture and previous urethral manipulation did not significantly impact the result of this surgical technique. LEVEL OF EVIDENCE: 4.


Subject(s)
Anastomosis, Surgical/methods , Urethral Stricture/surgery , Urologic Surgical Procedures, Male/methods , Adult , Aged , Aged, 80 and over , Follow-Up Studies , Humans , Male , Middle Aged , Plastic Surgery Procedures/methods , Retrospective Studies , Treatment Outcome , Urethral Stricture/etiology , Urethral Stricture/pathology , Young Adult
4.
Med. Afr. noire (En ligne) ; 63(9): 482-486, 2016. ilus
Article in French | AIM (Africa) | ID: biblio-1266211

ABSTRACT

Introduction : La principale indication de l'endoscopie digestive basse chez l'enfant est représentée par les rectorragies. Les polypes en constituent l'étiologie la plus fréquente. Notre objectif était de décrire les aspects épidémiologiques, cliniques, endoscopiques et histologiques des polypes recto-coliques chez l'enfant dans le centre d'endoscopie digestive du service d'hépato-gastroentérologie de l'hôpital Aristide Le Dantec de Dakar. Patients et méthode : Il s'agissait d'une étude rétrospective de janvier 2010 à décembre 2014. Tous les patients âgés de 0 à 15 ans qui présentaient des polypes recto-coliques à l'endoscopie digestive basse étaient inclus. Les données concernant l'âge et le sexe des patients, les indications, les conditions de l'examen, la nature des lésions, le geste thérapeutique réalisé ainsi que l'histologie des polypes ont été recueillis. Résultats : Nous avons inclus 13 patients. La prévalence des polypes recto-coliques était de 10,5%. L'âge moyen était de 5 ans. Il y avait 9 garçons et 4 filles (sex-ratio = 2,25). Les rectorragies constituaient la principale indication de l'endoscopie digestive basse (84,6%). Une moyenne de 1,5 polype par enfant était retrouvée. Le polype était solitaire dans 8 cas (61,5%). Il siégeait le plus souvent dans le rectum (69,2%). Une polypectomie a été réalisée dans 9 cas (69,2%) et une biopsie-exérèse à la pince froide dans 4 cas. Il s'agissait de polypes hamartomateux de type juvénile dans 11 cas (84,6%). Conclusion : Les rectorragies représentent la principale manifestation des polypes de l'enfant. Ces polypes sont le plus souvent de type hamartomateux. Le traitement repose essentiellement sur la polypectomie

5.
Ann Cardiol Angeiol (Paris) ; 64(1): 59-61, 2015 Feb.
Article in French | MEDLINE | ID: mdl-24095214

ABSTRACT

A significant proportion of the interindividual variability of the response to vitamin K antagonist (VKA) treatment has been associated with genetic factors. Genetic variations affecting the vitamin K epoxide reductase complex subunit 1 (VKORC1) are associated with hypersensitivity or rarely with resistance to VKA. We report the case of a black women patient who presents a resistance to acenocoumarol. Despite the use of high doses of acenocoumarol (114 mg/week) for the treatment of recurrent pulmonary embolism, the International Normalized Ratio was below the therapeutic target. This resistance to acenocoumarol was confirmed by the identification of a missense mutation Val66Met of the vitamin K epoxide reductase.


Subject(s)
Acenocoumarol/therapeutic use , Anticoagulants/therapeutic use , Drug Resistance/genetics , Mutation, Missense , Pulmonary Embolism/drug therapy , Vitamin K Epoxide Reductases/genetics , Adult , Female , Humans
6.
Prog Urol ; 24(10): 665-9, 2014 Sep.
Article in French | MEDLINE | ID: mdl-25214297

ABSTRACT

PURPOSE: To describe the epidemiological, anatomico-clinical and therapeutic aspects of the patent vaginoperitoneal canal (PVPC) in urological practice and to compare our results with those of pediatric teams. PATIENTS AND METHODS: We performed a retrospective descriptive study of PVPC cases operated in a urology unit. The following parameters were studied: medical history, age, method of installation, the anatomo-clinical type, side and the results of the treatment. RESULTS: A total of 163 cases were collected over a period of 5 years. The average age was 7.5 ± 7 years with a range of 2 months and 39 years. Thirty-four patients had less than or equal to age 2 ears and 28 patients were adults. The reason for consultation was an inguinal or scrotal inguinal, painless and intermittent swelling in 72.3% of cases. Installation mode was progressive in 45 patients (27.6%). The PVPC was sitting right in 81 patients (49.7%) and was bilateral in 12 patients (7.3%). The anatomo-clinical types were dominated by the communicating hydrocele (52%). The treatment was carried out in controlled surgery in all patients and the mean duration of hospitalization was 24 hours. The postoperative course was marked by 5 cases of scrotal hematoma and 2 cases of parietal suppuration. Postoperative mortality was zero. After a mean postoperative decrease of 2 years we observed 3 cases of testicular atrophy and two recurrences. CONCLUSION: Our results in terms of morbidity and mortality although satisfactory were lower than those of pediatric teams. LEVEL OF EVIDENCE: 5.


Subject(s)
Cysts/congenital , Cysts/surgery , Hernia, Inguinal/congenital , Hernia, Inguinal/surgery , Peritoneum/abnormalities , Peritoneum/surgery , Spermatic Cord , Testicular Hydrocele/congenital , Testicular Hydrocele/surgery , Adolescent , Child , Child, Preschool , Genital Diseases, Male/complications , Genital Diseases, Male/surgery , Humans , Infant , Male , Retrospective Studies , Urologic Surgical Procedures, Male/methods , Young Adult
7.
Prog Urol ; 24(6): 346-8, 2014 May.
Article in French | MEDLINE | ID: mdl-24821556

ABSTRACT

Scrotal calcinosis is a rare pathology and etiology still discussed. We report five cases in patients without particular history of another disease. Clinical examination revealed scrotal wall with painless nodules of various sizes producing a whitish substance, pasty. The phosphate levels were normal in all patients. They all had a resection of the lesions associated with scholarships plasty recovery. Histopathological study revealed calcified epidermoid cysts in 4 cases.


Subject(s)
Calcinosis/etiology , Epidermal Cyst/pathology , Genital Diseases, Male/pathology , Scrotum/pathology , Urologic Surgical Procedures, Male , Adult , Calcinosis/surgery , Epidermal Cyst/complications , Epidermal Cyst/surgery , Genital Diseases, Male/etiology , Genital Diseases, Male/surgery , Humans , Male , Middle Aged , Scrotum/surgery , Treatment Outcome , Urologic Surgical Procedures, Male/methods
8.
Prog Urol ; 24(1): 67-9, 2014 Jan.
Article in French | MEDLINE | ID: mdl-24365632

ABSTRACT

Bilharzioma are inflammatory pseudotumors, which often pose the problem of differential diagnosis with neoplastic processes. Using the keywords "testicular" and "schistosomiasis", there are only 14 cases of testicular bilharzioma identified on PubMed. The authors report two new cases in a 6-year-old child and an adult of 38 years, collected over a period of 5 years. In both cases, orchidectomy was performed and histological analysis of the surgical specimen was allowed to diagnose testicular bilharzioma by Schistosomia haematobium. The authors emphasize the need to evoke a bilharzioma before any testicular nodule in a patient living in an endemic area.


Subject(s)
Schistosomiasis haematobia , Testicular Diseases/parasitology , Adult , Child , Humans , Male , Schistosomiasis haematobia/diagnosis , Schistosomiasis haematobia/surgery , Testicular Diseases/diagnosis , Testicular Diseases/surgery
9.
Prog Urol ; 23(10): 884-9, 2013 Sep.
Article in French | MEDLINE | ID: mdl-24034801

ABSTRACT

OBJECTIVE: Describe the epidemiology, diagnosis and treatment of vesicovaginal fistula (VVF). PATIENTS AND METHODS: We conducted a retrospective descriptive study of all cases of VVF secondary to hysterectomy. The following parameters were studied: age, parity, indication for hysterectomy, risk factors, the consultation period, the anatomical type of VVF, the paraclinical, the surgical approach and results of the cure. RESULTS: Fourteen cases were identified over 10 years. All hysterectomies were performed by laparotomia. The average age of patients was 54.3±13 years. Hysterectomy was performed in view of a uterine leiomyoma in eight cases, a cancer of the cervix in four cases, a menometrorrhagia in one case and a choriocarcinoma in one case. Four patients had received neoadjuvant radiotherapy. The mean time from injury was 13.5±18 months. Examination under valve was allowed to find 11 VVF type 1 and three type 2 VVF. IVU was normal in seven patients and allowed to find an ureterohydronephrose stage III in one patient. VVF was addressed by high in ten cases including 5 by transperitoneovaginale and 5 by transvesical pure. The postoperative course was uneventful in 11 patients (78%) but marked by vesicocutaneous fistula, parietal suppuration and one failure. CONCLUSION: In this short series of post-hysterectomy VVF treated by laparotomia, we observed a rate of cure satisfying in spite of an important psychosocial morbidity.


Subject(s)
Hysterectomy/adverse effects , Vesicovaginal Fistula/etiology , Adult , Aged , Choriocarcinoma/therapy , Female , Humans , Leiomyoma/surgery , Middle Aged , Parity , Radiotherapy, Adjuvant/statistics & numerical data , Retrospective Studies , Risk Factors , Time-to-Treatment , Uterine Cervical Neoplasms/therapy , Uterine Neoplasms/surgery , Vesicovaginal Fistula/surgery
10.
Prog Urol ; 22(16): 1010-4, 2012 Dec.
Article in French | MEDLINE | ID: mdl-23178097

ABSTRACT

OBJECTIVES: To evaluate the results of Anderson-Hynes open pyeloplasty in our institution. And then to compare them to those of laparoscopic procedure and identify what can be considered now as the indications of the open procedure. PATIENTS AND METHODS: It was a retrospective study on 30 cases of ureteropelvic junction syndrome managed by Anderson-Hynes open procedure. The clinical, biological and radiologic characteristics of the patients as well as the surgical technique and its results were taken into account. The patients were classified, according to Valdeyer and Cendron classification as type II in eight cases (26.7%), type III in ten cases (33.3%) and type IV in four cases (13.3%). There were also eight cases of giant hydronephrosis (26.7%). The operating time, the length of hospital stay and the outcomes were studied and compared with those of the laparoscopic pyeloplasty found in the medical literature. RESULTS: The mean operating time was 115 ± 33.4 minutes (90-230 min). The mean length of hospital stay was 10.4 ± 5.1 days. Six patients (20%) had postoperative complications. After a mean follow-up of 28 ± 13.7 months (13-48 months), our first-hand success rate was 90% (n=27). CONCLUSION: Anderson-Hynes open pyeloplasty reached good results but nowadays its indications can be limited to laparoscopic contraindications, severe hydronephrosis (grade IV or giant hydronephrosis) and second-hand cases. The two latter indications depend on the surgeon experience in laparoscopic surgery.


Subject(s)
Hydronephrosis/surgery , Kidney Pelvis/surgery , Laparoscopy , Ureteral Obstruction/surgery , Urologic Surgical Procedures/methods , Adolescent , Adult , Child , Child, Preschool , Dilatation, Pathologic , Female , Follow-Up Studies , Humans , Hydronephrosis/diagnosis , Kidney Pelvis/pathology , Laparoscopy/methods , Length of Stay , Male , Middle Aged , Retrospective Studies , Severity of Illness Index , Syndrome , Time Factors , Treatment Outcome
11.
Int J Gen Med ; 4: 561-9, 2011.
Article in English | MEDLINE | ID: mdl-21887109

ABSTRACT

BACKGROUND: Parkinson's disease (PD) is a chronic neurodegenerative disorder. There is limited knowledge about the function of the hypothalamic-pituitary-adrenal axis in PD. The primary aim of this prospective study was to analyze diurnal salivary cortisol concentrations in patients with PD and correlate these with age, gender, body mass index (BMI), duration of PD, and pain. The secondary aim was to compare the results with a healthy reference group. METHODS: Fifty-nine PD patients, 35 women and 24 men, aged 50-79 years, were recruited. The reference group comprised healthy individuals matched for age, gender, BMI, and time point for sampling. Salivary cortisol was collected at 8 am, 1 pm, and 8 pm, and 8 am the next day using cotton-based Salivette(®) tubes and analyzed using Spectria(®) Cortisol I(125). A visual analog scale was used for estimation of pain. RESULTS: The median cortisol concentration was 16.0 (5.8-30.2) nmol/L at 8 am, 5.8 (3.0-16.4) at 1 pm, 2.8 (1.6-8.0) at 8 pm, and 14.0 (7.5-28.7) at 8 am the next day. Total secretion and rate of cortisol secretion during the day (8 am-8 pm) and the concentration of cortisol on the next morning were lower (12.5 nmol/L) in the reference group. No significant correlations with age, gender, BMI, duration of PD, Hoehn and Yahr score, Unified Parkinson's Disease Rating Scale III score, gait, pain, or cortisol concentrations were found. CONCLUSION: The neurodegenerative changes in PD does not seem to interfere with the hypothalamic-pituitary-adrenal axis. Salivary cortisol concentrations in PD patients were increased in the morning compared with the reference group, and were not influenced by motor dysfunction, duration of disease, or coexistence of chronic or acute pain.

12.
Prog Urol ; 21(8): 521-6, 2011 Sep.
Article in French | MEDLINE | ID: mdl-21872154

ABSTRACT

OBJECTIVE: To study current epidemiological and clinical features of adult renal cancer in Senegal and the evolution of these features over the two past decades. PATIENTS AND METHODS: We conducted a retrospective ten years study (2000-2009) that analyzed all the renal cell cancer in adult admitted in the urology department and the pathology department of the university teaching hospital Aristide-Le-Dantec (Dakar). The results of this study were compared with those of the previous decade. RESULTS: We included 74 cases of renal cell cancer. The median age of patients was 49 years (18-72 years). There was a slight female predominance (51.3%). Twenty-eight (37.8%) patients presented at least with one renal cell cancer risk factor. The median duration of symptoms was 10 months (1-96 months). The localization of the renal cancer was right in 42 patients (56.7%) and left in 32 cases (43.8%). Almost all the tumors were symptomatic. Symptoms were dominated by loin pain (87.8%) and abdominal mass (77%). There were only two cases (2.7%) of incidental renal cell cancer. The median tumor size was 12 cm (2.4-26 cm). The more frequent tumor stages according to the TNM 2002 staging system were T2 (39.2%) and T3 (33.7%). Metastases were found in 23 (31%) patients. Forty-four patients underwent nephrectomy (43 radical and one partial). No adjuvant treatment or metastasectomy were done. The main histological subtype of tumors was renal cell carcinoma (47 cases). The mean duration of the follow up was 30.5 ± 33.6 months. Among the 44 patients who underwent nephrectomy, no tumor recurrence was found on 35 cases. Tumor recurrence occurred on nine patients. The specific mortality rate was 47.3%. Epidemiological and clinical features of the adult renal cell cancer in Senegal haven't significantly changed over the 20 past years. CONCLUSION: The adult renal cell cancer incidence was low in Senegal. Its clinical profile was characterized by a predominance of locally advanced and metastatic forms.


Subject(s)
Carcinoma, Renal Cell/diagnosis , Carcinoma, Renal Cell/epidemiology , Kidney Neoplasms/diagnosis , Kidney Neoplasms/epidemiology , Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged , Retrospective Studies , Senegal/epidemiology , Time Factors , Young Adult
13.
Arch Pediatr ; 18(5): 537-9, 2011 May.
Article in French | MEDLINE | ID: mdl-21458970

ABSTRACT

Renal cell carcinoma (RCC) in children is rare. This entity has different clinical and biological presentation characteristics from adult RCC. In contrast to Wilms tumor, the efficacy of chemotherapy and radiation therapy in pediatric RCC remains uncertain. Debate continues on the importance of lymph node dissection. The authors present a case of RCC with lymph node involvement in a 12-year-old boy. The treatment was radical nephrectomy and a limited lymphadenectomy. No adjuvant therapy was given. After 13 months of follow-up, there is no evidence of recurrence. This case shows that lymph node involvement (in the absence of distant metastases) is not associated with a poor prognosis in pediatric RCC and that lymphadenectomy in lymph node-positive cases is important.


Subject(s)
Carcinoma, Renal Cell , Kidney Neoplasms , Carcinoma, Renal Cell/secondary , Carcinoma, Renal Cell/surgery , Child , Humans , Kidney Neoplasms/pathology , Kidney Neoplasms/surgery , Lymphatic Metastasis , Male , Nephrectomy
14.
Med Trop (Mars) ; 71(6): 588-90, 2011 Dec.
Article in French | MEDLINE | ID: mdl-22393626

ABSTRACT

Adult-onset Still's disease is a uncommon form of inflammatory rheumatism. It has rarely been reported in black Africa. The purpose of this report is to describe a case in a 49-year-old woman from Dakar, Senegal.


Subject(s)
Still's Disease, Adult-Onset/diagnosis , Anti-Inflammatory Agents/therapeutic use , Female , Fever/diagnosis , Fever/drug therapy , Fever/etiology , Humans , Middle Aged , Prednisone/therapeutic use , Senegal , Still's Disease, Adult-Onset/complications , Still's Disease, Adult-Onset/drug therapy
15.
Med Trop (Mars) ; 71(5): 495-8, 2011 Oct.
Article in French | MEDLINE | ID: mdl-22235626

ABSTRACT

PURPOSE: To report epidemiological, clinical and paraclinical features of pyonephrosis and describe current management methods in Senegal. PATIENTS AND METHODS: This retrospective study includes a series of patients admitted for pyonephrosis to the Urology Department of the Aristide Le Dantec Hospital in Dakar between 1995 and 2009. The following information was collected for each patient: age, sex, clinical manifestations, diagnostic findings, treatment modalities and outcomes. RESULTS: A total of 44 patients with a mean age of 34 years were included. The most common clinical manifestations were acute flank pain, sepsis and renal mass. Diagnostic was usually based on medical imaging, i.e., renal utrasonography and computed tomography. Urolithiasis was the underlying etiology in 73.2% of cases. Nephrectomy was performed in 83% of cases with or without preliminary nephrostomy catheterization. CONCLUSION: Development of both diagnostic (medical imaging) and therapeutic methods for management of pyonephrosis has been consistent with the rarity of this condtion in Senegal.


Subject(s)
Pyonephrosis/diagnosis , Pyonephrosis/therapy , Adolescent , Adult , Aged , Anti-Bacterial Agents/therapeutic use , Child , Child, Preschool , Diagnostic Imaging , Female , Flank Pain/etiology , Humans , Male , Middle Aged , Nephrectomy/statistics & numerical data , Pyonephrosis/etiology , Retrospective Studies , Senegal/epidemiology , Sepsis/etiology , Urolithiasis/complications , Young Adult
16.
Lett Appl Microbiol ; 50(4): 357-61, 2010 Apr.
Article in English | MEDLINE | ID: mdl-20132434

ABSTRACT

AIMS: To investigate the antimicrobial spectrum of Lactococcus piscium CNCM I-4031 and its protective effect in cooked and peeled shrimp against Brochothrix thermosphacta. METHODS AND RESULTS: Sixteen pathogenic and spoiling bacteria were inhibited in Elliker, but not in shrimp juice agar plates. In shrimp packed under modified atmosphere and stored at 8 degrees C, B. thermosphacta (10(3) CFU g(-1)) was inhibited by 4.1 log CFU g(-1) when co-inoculated with L. piscium (10(6) CFU g(-1)). Brochothrix thermosphacta spoiled the product after 11 days, with the emission of strong butter/caramel off-odours. In co-culture with L. piscium, sensory shelf-life was extended by at least 10 days. The inhibition was partially explained by a drop in pH from 6.6 to 5.6. The physicochemical composition of shrimp and shrimp juice was established to identify the inhibition mechanisms involved. CONCLUSION: Lactococcus piscium CNCM I-4031 has a wide antimicrobial spectrum. The strain inhibits B. thermosphacta in shrimp and significantly prolongs sensory shelf-life. SIGNIFICANCE AND IMPACT OF THE STUDY: Lactococcus piscium CNCM I-4031 is shown to be a promising agent for improving shrimp quality and may be tested against pathogens and in other food matrices. Knowledge of the physicochemical composition of shrimp and shrimp juice will allow the development of a chemically defined model medium for determining the inhibition mechanisms involved.


Subject(s)
Bacteria/growth & development , Food Contamination/prevention & control , Food Microbiology , Lactococcus/growth & development , Shellfish/microbiology , Antibiosis , Coculture Techniques , Culture Media , Food Handling , Shellfish/analysis
17.
Prog Urol ; 22(6): 344-9, 2010 May.
Article in French | MEDLINE | ID: mdl-22541904

ABSTRACT

PURPOSE: To report the oncologic results and morbidity of bilateral pulpectomy and to identify factors that make this method of androgen suppression therapy the most used in our country. PATIENTS AND METHODS: We conducted a prospective study in the urology department of Aristide Le-Dantec hospital (Dakar) between January 2008 and June 2010 (30 months). It included 84 cases of prostate cancer treated by bilateral pulpectomy under local anesthesia. RESULTS: The mean age of patients was 72.17±12.48 years (53-91). The median PSA level was 101 ng/mL (12.18-9990). Metastasis have been detected in 75% of cases. The Gleason score was higher than 7 in 40 patients (47.6%). Three months after pulpectomy, an improvement of performance status was seen in 76 patients (90.4%). The back pain significantly decreased in intensity or disappeared in 65.3% (32/49) of cases. A complete recovery of lower limbs motor deficit was observed in 50% of cases (7/14). The PSA levels decreased in 57 of the 76 patients alive and the mean PSA level was then 72±11.7 ng/mL (3.8-2433). At six months, of the 53 patients in urinary retention, 18 had recovered spontaneous and complete urination. The PSA level was below 4 ng/mL in 33.8% (22/65) of cases and between 4 and 10 ng/mL in 52.3% (34/65) of cases. At 12 months, the median PSA nadir was 0.76 ng/mL (0,002-8,17) and 57.4% of the 54 patients alive had a PSA nadir less than 2 ng/mL. The mean follow-up was 11.08±10.34 months (1-30). A rising PSA occurred in 17 patients (20.2%) after an mean progression-free survival of 10.5 months (6-25). The overall survival at 6, 12 and 24 months were respectively 77.3, 64.3 and 52.3%. The overall cost of pulpectomy was 50 000 FCFA (76€). The specific morbidity of pulpectomy was two cases (2.4%) of infection of the operative site. CONCLUSION: The bilateral pulpectomy was a method of androgen suppression immediately effective, efficacious with a low morbidity. Its very low cost is the main reason why it is still the most used method in our country.


Subject(s)
Orchiectomy/methods , Prostatic Neoplasms/surgery , Aged , Aged, 80 and over , Humans , Male , Middle Aged , Prospective Studies
18.
Med Trop (Mars) ; 70(5-6): 475-8, 2010 Dec.
Article in French | MEDLINE | ID: mdl-21520650

ABSTRACT

UNLABELLED: To describe clinical and therapeutic features of ischemic priapism associated with sickle cell disease (SSD) in Senegalese men and to identify risk factors for erectile dysfunction (ED). PATIENTS AND METHODS: The charts of all patients admitted to the Urology Department of Aristide Le Dantec University Teaching Hospital (Dakar) for ischemic priapism associated with SSD between January 2000 and September 2008 were retrospectively reviewed. RESULTS: A total of 22 patients with a mean age of 19.5 +/- 9.9 years (6 - 41 years) were identified. The most affected age group was between 21 and 30 years. The mean duration between onset of the episode and admission was 89.6 +/- 103.1 hours (4 - 384 hours). Nine patients (40.9%) were admitted within 24 hours after the onset. Eight patients (36.3%) had a history of stuttering priapism. The sickle cell phenotype identified by electrophoresis was SS in 18 patients and AS in four. The main treatment modalities were corporeal aspiration that was performed with or without intracavernosal injection of sympathomimetics drugs and Al Ghorab shunt surgery that was used in ten patients with a success rate of 90 % (complete detumescence). With a mean follow-up of 3.8 +/- 1.5 years, nine (69.2%) of the 13 patients older than 16 years developed ED. The incidence of ED was significantly correlated with the duration of the priapism but not with SSD phenotype. CONCLUSION: In Senegal ischemic priapism associated with sickle cell disease occurs mainly in young people. The incidence of ischemic priapism appears to be low but ED is common due to the prolonged duration of priapism.


Subject(s)
Anemia, Sickle Cell/complications , Erectile Dysfunction/etiology , Priapism/etiology , Acute Disease , Adolescent , Adult , Child , Follow-Up Studies , Humans , Male , Retrospective Studies , Risk Factors , Senegal , Young Adult
19.
Mali Med ; 25(4): 43-6, 2010.
Article in French | MEDLINE | ID: mdl-21470948

ABSTRACT

PURPOSE: To report the cases of urolithiasis in children and to assess epidemiological, clinical and therapeutically aspects. PATIENTS AND METHODS: We study retrospectively the cases of urolithiasis in children of 0 to 15 years old between 2003 and 2008. The parameters of study were: age, sex, clinical and therapeutically aspects. RESULTS: We report 20 cases. The mean age was 5.4 years. The sex-ratio was 9/1. Dysuria was the most common symptom. Abdominal plain radiography associate with ultrasonography permitted the diagnostic in most cases. Stone location was in the bladder mainly (n = 12). Posterior Urethra valves were the common etiology found. The surgical treatment was performed in all cases and consisted of cystolithotomy in the majority. CONCLUSION: Children urinary stones are less common than in adults. The etiologies are different but the treatment is coming to be alike.


Subject(s)
Urolithiasis/diagnosis , Urolithiasis/therapy , Abdominal Pain , Adolescent , Child , Child, Preschool , Dysuria/etiology , Female , Humans , Infant , Infant, Newborn , Lithotripsy , Male , Retrospective Studies
20.
Prog Urol ; 19(2): 101-6, 2009 Feb.
Article in French | MEDLINE | ID: mdl-19168012

ABSTRACT

OBJECTIVE: To assess the feasibility of selective clamping of segmental renal arteries during partial nephrectomy, in order to limit renal infarction to the pathological area to be resected. MATERIALS AND METHODS: A dissection of renal artery and its extraparenchymal branches was realised. The study included 30 kidneys from recent nonformolised corpses. The size, distribution, and accessibility of the arteries were considered. All the corpses underwent a lombotomy with or without rib resection. RESULTS: The majority of dissected kidneys had a unique artery (96.66% of cases). The number of segmental arteries was zero in five cases (16.66%), one in four cases (13.33%), two in four cases (13.33%), three in one case (3%), four in 15 cases (50%) and five in five cases (16.66%). The posterior and inferior segmental arteries were more accessible to isolate with a respective ratio of 94 and 100% at segmental level. Apical and middle segmental arteries were least accessible with a respective ratio of 73 and 80%. The majority of accidents during dissection occurred with the middle segmental artery (62.5% of vascular lesions). CONCLUSION: This anatomic dissection on corpses showed that selective renal segmental arteries is possible in the majority of cases. This dissection is better indicated in partial nephrectomies for renal tumours located posteriorly or in the lower pole.


Subject(s)
Nephrectomy/methods , Renal Artery , Adult , Cadaver , Constriction , Feasibility Studies , Female , Humans , Male
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