Cancer-Net SCa: tailored deep neural network designs for detection of skin cancer from dermoscopy images.

BACKGROUND: Skin cancer continues to be the most frequently diagnosed form of cancer in the U.S., with not only significant effects on health and well-being but also significant economic costs associated with treatment. A crucial step to the treatment and management of skin cancer is effective early detection with key screening approaches such as dermoscopy examinations, leading to stronger recovery prognoses. Motivated by the advances of deep learning and inspired by the open source initiatives in the research community, in this study we introduce Cancer-Net SCa, a suite of deep neural network designs tailored for the detection of skin cancer from dermoscopy images that is open source and available to the general public. To the best of the authors' knowledge, Cancer-Net SCa comprises the first machine-driven design of deep neural network architectures tailored specifically for skin cancer detection, one of which leverages attention condensers for an efficient self-attention design. RESULTS: We investigate and audit the behaviour of Cancer-Net SCa in a responsible and transparent manner through explainability-driven performance validation. All the proposed designs achieved improved accuracy when compared to the ResNet-50 architecture while also achieving significantly reduced architectural and computational complexity. In addition, when evaluating the decision making process of the networks, it can be seen that diagnostically relevant critical factors are leveraged rather than irrelevant visual indicators and imaging artifacts. CONCLUSION: The proposed Cancer-Net SCa designs achieve strong skin cancer detection performance on the International Skin Imaging Collaboration (ISIC) dataset, while providing a strong balance between computation and architectural efficiency and accuracy. While Cancer-Net SCa is not a production-ready screening solution, the hope is that the release of Cancer-Net SCa in open source, open access form will encourage researchers, clinicians, and citizen data scientists alike to leverage and build upon them.

Fibrosis-Net: A Tailored Deep Convolutional Neural Network Design for Prediction of Pulmonary Fibrosis Progression From Chest CT Images.

Pulmonary fibrosis is a devastating chronic lung disease that causes irreparable lung tissue scarring and damage, resulting in progressive loss in lung capacity and has no known cure. A critical step in the treatment and management of pulmonary fibrosis is the assessment of lung function decline, with computed tomography (CT) imaging being a particularly effective method for determining the extent of lung damage caused by pulmonary fibrosis. Motivated by this, we introduce Fibrosis-Net, a deep convolutional neural network design tailored for the prediction of pulmonary fibrosis progression from chest CT images. More specifically, machine-driven design exploration was leveraged to determine a strong architectural design for CT lung analysis, upon which we build a customized network design tailored for predicting forced vital capacity (FVC) based on a patient's CT scan, initial spirometry measurement, and clinical metadata. Finally, we leverage an explainability-driven performance validation strategy to study the decision-making behavior of Fibrosis-Net as to verify that predictions are based on relevant visual indicators in CT images. Experiments using a patient cohort from the OSIC Pulmonary Fibrosis Progression Challenge showed that the proposed Fibrosis-Net is able to achieve a significantly higher modified Laplace Log Likelihood score than the winning solutions on the challenge. Furthermore, explainability-driven performance validation demonstrated that the proposed Fibrosis-Net exhibits correct decision-making behavior by leveraging clinically-relevant visual indicators in CT images when making predictions on pulmonary fibrosis progress. Fibrosis-Net is able to achieve a significantly higher modified Laplace Log Likelihood score than the winning solutions on the OSIC Pulmonary Fibrosis Progression Challenge, and has been shown to exhibit correct decision-making behavior when making predictions. Fibrosis-Net is available to the general public in an open-source and open access manner as part of the OpenMedAI initiative. While Fibrosis-Net is not yet a production-ready clinical assessment solution, we hope that its release will encourage researchers, clinicians, and citizen data scientists alike to leverage and build upon it.

OutlierNets: Highly Compact Deep Autoencoder Network Architectures for On-Device Acoustic Anomaly Detection.

Human operators often diagnose industrial machinery via anomalous sounds. Given the new advances in the field of machine learning, automated acoustic anomaly detection can lead to reliable maintenance of machinery. However, deep learning-driven anomaly detection methods often require an extensive amount of computational resources prohibiting their deployment in factories. Here we explore a machine-driven design exploration strategy to create OutlierNets, a family of highly compact deep convolutional autoencoder network architectures featuring as few as 686 parameters, model sizes as small as 2.7 KB, and as low as 2.8 million FLOPs, with a detection accuracy matching or exceeding published architectures with as many as 4 million parameters. The architectures are deployed on an Intel Core i5 as well as a ARM Cortex A72 to assess performance on hardware that is likely to be used in industry. Experimental results on the model's latency show that the OutlierNet architectures can achieve as much as 30× lower latency than published networks.