[Immune response to vaccination by Grippol in female northerners from Arkhagel'sk]. / Immunnyi otvet vaktsinirovannykh "Grippolom" zhenshchin-severianok, zhitel'nits Arkhangel'ska.

The immune-system condition of virtually healthy subjects (aged 35-45) was studied before vaccination ("Grippol") and 1 week later. An intense formation of antibodies to virus hemagglutinin is associated with lymphoproliferative reaction combined with differentiation of immune-competent cells (ICC) and with a higher phagocyte activity. A lack of any changed reactions to the administered antigen is interrelated with a deficit of phagocyte protection and with an activated ICC apoptosis.

[The detection of atypical human rotaviruses and their characteristics]. / Obnaruzhenie atipichnykh rotavirusov cheloveka i ikh kharakteristika.

The electrophoretic typing of 1,370 rotavirus strains revealed the presence of group C rotaviruses in 1.3% of cases. In the Arkhangelsk region group C rotaviruses were detected in 34.4% of cases. The detected group C rotaviruses were shown to be no different in their morphology from typical ones; they were characterized by the variability of their genome and the absence of hybridization with RNA of group A rotaviruses. Group C rotaviruses were detected in children aged 3-6 years; in this age group they caused both sporadic morbidity and an outbreak of infection. The clinical manifestations of gastroenteritis caused by group C rotaviruses were no different from typical rotavirus gastroenteritis.