A Novel Enhancement Approach Following MVMD and NMF Separation of Complex Snoring Signals.

Snoring is a prominent characteristic of sleep-disordered breathing, and its detection is critical for determining the severity of the upper airway obstruction and improving daily quality of life. Home snoring analysis is a highly invasive method, but it becomes challenging when a sleeping partner also snores, leading to distorted evaluations in such environments. In this article, we tackle the problem of complex snore signal separation of multiple snorers. This article introduces two audio-based methods that efficiently extract an individual's snoring signal, allowing for the analysis of sleep-breathing disorders in a normal sleeping environment without isolating individuals. In the first method, Principal Component Analysis (PCA) identifies the source components from the finite number of modes generated by the decomposition of the snoring mixture using Multivariate Variational Mode Decomposition (MVMD). The second method applies Blind Source Separation (BSS) based on Non-Negative Matrix Factorization (NMF) to separate the single-channel snoring mixture. Furthermore, the decomposed signals are tuned using the iterative enhancement algorithm to adequately match the source snoring signals. These methods were evaluated by simulating various real-time snoring recordings of 7 subjects (2 men, 2 women, and 3 children). The correlation coefficient between the source and its separated signal was computed to assess the separation results, exhibiting good performance of the methods used. The enhancement approach also demonstrated its efficiency by increasing the correlation over to 80% in both methods. The experimental results show that the proposed algorithms are effective and practical for separating mixed snoring signals.

A systematic review on functional electrical stimulation based rehabilitation systems for upper limb post-stroke recovery.

Background: Stroke is one of the most common neurological conditions that often leads to upper limb motor impairments, significantly affecting individuals' quality of life. Rehabilitation strategies are crucial in facilitating post-stroke recovery and improving functional independence. Functional Electrical Stimulation (FES) systems have emerged as promising upper limb rehabilitation tools, offering innovative neuromuscular reeducation approaches. Objective: The main objective of this paper is to provide a comprehensive systematic review of the start-of-the-art functional electrical stimulation (FES) systems for upper limb neurorehabilitation in post-stroke therapy. More specifically, this paper aims to review different types of FES systems, their feasibility testing, or randomized control trials (RCT) studies. Methods: The FES systems classification is based on the involvement of patient feedback within the FES control, which mainly includes "Open-Loop FES Systems" (manually controlled) and "Closed-Loop FES Systems" (brain-computer interface-BCI and electromyography-EMG controlled). Thus, valuable insights are presented into the technological advantages and effectiveness of Manual FES, EEG-FES, and EMG-FES systems. Results and discussion: The review analyzed 25 studies and found that the use of FES-based rehabilitation systems resulted in favorable outcomes for the stroke recovery of upper limb functional movements, as measured by the FMA (Fugl-Meyer Assessment) (Manually controlled FES: mean difference = 5.6, 95% CI (3.77, 7.5), P < 0.001; BCI-controlled FES: mean difference = 5.37, 95% CI (4.2, 6.6), P < 0.001; EMG-controlled FES: mean difference = 14.14, 95% CI (11.72, 16.6), P < 0.001) and ARAT (Action Research Arm Test) (EMG-controlled FES: mean difference = 11.9, 95% CI (8.8, 14.9), P < 0.001) scores. Furthermore, the shortcomings, clinical considerations, comparison to non-FES systems, design improvements, and possible future implications are also discussed for improving stroke rehabilitation systems and advancing post-stroke recovery. Thus, summarizing the existing literature, this review paper can help researchers identify areas for further investigation. This can lead to formulating research questions and developing new studies aimed at improving FES systems and their outcomes in upper limb rehabilitation.

Validation of Screen-Printed Electronic Skin Based on Piezoelectric Polymer Sensors.

This paper proposes a validation method of the fabrication technology of a screen-printed electronic skin based on polyvinylidene fluoride-trifluoroethylene P(VDF-TrFE) piezoelectric polymer sensors. This required researchers to insure, through non-direct sensor characterization, that printed sensors were working as expected. For that, we adapted an existing model to non-destructively extract sensor behavior in pure compression (i.e., the d33 piezocoefficient) by indentation tests over the skin surface. Different skin patches, designed to sensorize a glove and a prosthetic hand (11 skin patches, 104 sensors), have been tested. Reproducibility of the sensor response and its dependence upon sensor position on the fabrication substrate were examined, highlighting the drawbacks of employing large A3-sized substrates. The average value of d33 for all sensors was measured at incremental preloads (1-3 N). A systematic decrease has been checked for patches located at positions not affected by substrate shrinkage. In turn, sensor reproducibility and d33 adherence to literature values validated the e-skin fabrication technology. To extend the predictable behavior to all skin patches and thus increase the number of working sensors, the size of the fabrication substrate is to be decreased in future skin fabrication. The tests also demonstrated the efficiency of the proposed method to characterize embedded sensors which are no more accessible for direct validation.

Dual-Parameter Modulation Improves Stimulus Localization in Multichannel Electrotactile Stimulation.

Among most challenging open issues in prosthetic research is the development of a robust bidirectional interface between a prosthesis and its user. Commercially available prosthetic systems are mechanically advanced, but they do not provide somatosensory feedback. Here, we present a novel non-invasive interface for multichannel electrotactile feedback, comprising a matrix of 24 pads, and we investigate the ability of able-bodied human subjects to localize the electrotactile stimulus delivered through the matrix. For this purpose, we tested conventional stimulation (same frequency for all pads) and a novel dual-parameter modulation scheme (interleaved frequency and intensity) designed to facilitate the spatial localization over the electrode. Electrotactile stimulation was also compared to mechanical stimulation of the same locations on the skin. Experimental results on eight able-bodied subjects demonstrated that the proposed interleaved coding substantially improved the spatial localization compared to same-frequency stimulation. The results also showed that same-frequency stimulation was equivalent to mechanical stimulation, whereas the performance with dual-parameter modulation was significantly better. These are encouraging outcomes for the application of a multichannel interface for the restoration of feedback in prosthetics. The high-resolution augmented interfaces might be used to explore novel scenarios for effective communication with the prosthesis user enabled by maximizing information transmission.