Recurrent Erythema Multiforme Major Following COVID-19 Infection.

Erythema multiforme (EM) is a rare and potentially serious skin condition that can present as a myriad of mucocutaneous lesions. EM can be commonly confused with other cutaneous etiologies, leading to misdiagnosis and delay in proper treatment. This paper describes a case of recurrent erythema multiforme following COVID-19 infection in a 34-year-old male with no prior medical history. The patient had an extensive rash of the oral and genital mucosal areas, diffuse cutaneous involvement, and an extended length of recovery. This unexpected association of EM and COVID-19 provides additional insight into the limited research available regarding the correlation between these two pathologies.

Idiopathic Granulomatous Mastitis Presenting in a Patient With Hypothyroidism and Recent Hospitalization for Myxedema Coma: A Rare Case Report and Review of Literature.

Idiopathic granulomatous mastitis (IGM) is a rare, benign inflammatory disorder of the breast. Clinical features may include painful breasts, erythema, subcutaneous nodules, and ulcerative lesions. It can mimic various other breast pathologies, and it is a diagnosis of exclusion after infection, malignancy, and other inflammatory conditions have been ruled out. In this article, we present a case of IGM developing in a 40-year-old female 3 months after hospitalization for myxedema coma. A contrast-enhanced magnetic resonance imaging of the breasts showed bilateral edema, and a biopsy was negative for malignancy or infection. She was started on prednisone and had noticeable improvement of ulcerations within several weeks. IGM is a rare condition that requires a multimodal treatment approach. Often recalcitrant disease is encountered and requires surgical intervention, immunosuppression, and antimicrobial therapy. The diagnosis should be entertained in patients with bilateral breast inflammation to avoid unnecessary surgical resection early on.

QTc prolongation due to propranolol overdose.

Prolongation of the QTc interval (a QT interval that has been corrected for heart rate) increases the risk of cardiac arrhythmias, and is an important topic with regard to psychotropic medication. Several typical (e.g., pimozide, thioridazine, haloperidol) and atypical (e.g., sertindole, ziprasidone) antipsychotics may cause QTc prolongation as well as some antidepressants in overdose (e.g., citalopram). We wish to present a case of QTc prolongation that was due to an overdose of propranolol (used in psychiatry for the treatment of akathisia, lithium-induced tremor, and performance anxiety; used in medicine for hypertension and congestive heart failure).