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1.
Materials (Basel) ; 14(17)2021 Aug 30.
Article in English | MEDLINE | ID: mdl-34501021

ABSTRACT

This work applies a procedure for analysis and characterization of the surface of brake friction materials, correlating them with the tribological and thermal properties achieved in different vehicle braking conditions. Experiments were performed in a vehicle under two real conditions of braking operation, simulated flat track descent and emergency braking. Characteristics of the plates formed on the surfaces of the friction materials were analyzed by scanning electron microscopy (SEM) and correlated with the performance during braking, as measured by the coefficient of friction at the interface of the friction pair and temperature. As a result, the formation of the primary and secondary plateaus in these two different braking operating conditions was observed, and the relationship between the characteristics of the plateaus formed on the surface and the surface roughness parameters and performance measurements during braking.

2.
Int J Biol Macromol ; 126: 359-366, 2019 Apr 01.
Article in English | MEDLINE | ID: mdl-30572056

ABSTRACT

The combination of bismuth(III) citrate and the antibiotic furazolidone (FDZ) results in a synergetic effect on Helicobacter pylori eradication. However, the problems associated with their oral administration are challenges to overcome. Thus, in the present study, sodium alginate (SA)/carboxymethyl cellulose (CMC) blend hydrogels (SC) were developed for concomitant and controlled release of furazolidone and bismuth(III). The blank formulation (SCblank) and the three drug-loaded hydrogels (SCFDZ, SCBi, and SCFDZ-Bi) were prepared by casting method and characterized by infrared spectroscopy, scanning electron microscopy, differential scanning calorimetry, and X ray powder diffraction analyses. The swelling equilibrium and cumulative release amounts of FDZ and Bi3+ have indicated distinct behaviors of the hydrogels to different pH values. The bismuth-containing sample (SCFDZ-Bi) presents more resistance to degradation on a neutral solution and shows more suitable properties for controlled drug release than the sample without bismuth (SCFDZ). Microbiological studies, using Escherichia coli as a model, show bacteria viability reduction in presence of the drug-loaded samples. The developed system containing furazolidone and bismuth(III) appears to be promising for oral administration with concomitant and controlled release of these drugs aimed at the pharmacological treatment of gastrointestinal disorders.


Subject(s)
Alginates/chemistry , Bismuth/pharmacology , Carboxymethylcellulose Sodium/chemistry , Cross-Linking Reagents/chemistry , Furazolidone/pharmacology , Anti-Bacterial Agents/pharmacology , Calorimetry, Differential Scanning , Delayed-Action Preparations/pharmacology , Drug Liberation , Escherichia coli/drug effects , Hydrogels/chemistry , Microbial Sensitivity Tests , Spectroscopy, Fourier Transform Infrared , Water/chemistry , X-Ray Diffraction
3.
Materials (Basel) ; 9(9)2016 Sep 13.
Article in English | MEDLINE | ID: mdl-28773895

ABSTRACT

Composite materials are widely employed in the naval, aerospace and transportation industries owing to the combination of being lightweight and having a high modulus of elasticity, strength and stiffness. Drilling is an operation generally used in composite materials to assemble the final product. Damages such as the burr at the drill entrance and exit, geometric deviations and delamination are typically found in composites subjected to drilling. Drills with special geometries and pilot holes are alternatives used to improve hole quality as well as to increase tool life. The present study is focused on the drilling of a sandwich composite material (two external aluminum plates bound to a polyethylene core). In order to minimize thrust force and burr height, the influence of drill geometry, the pilot hole and the cutting parameters was assessed. Thrust force and burr height values were collected and used to perform an analysis of variance. The results indicated that the tool and the cutting speed were the parameters with more weight on the thrust force and for burr height they were the tool and the interaction between tool and feed. The results indicated that drilling with a pilot hole of Ø4 mm exhibited the best performance with regard to thrust force but facilitated plastic deformation, thus leading to the elevation of burr height, while the lowest burr height was obtained using the Brad and Spur drill geometry.

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