ABSTRACT
Barrett's esophagus is defined as a disorder in which the normal stratified squamous mucosa of the esophagus is replaced by columnar epithelium. Patients with Barrett's esophagus are at risk to develop an adenocarcinoma of the esophagus. Pathologic gastroesophageal reflux is correlated to the disease and therapeutical options must aim to stop this noxa in order to prevent columnar metaplasia, and subsequent dysplasia and/or neoplasia. The Authors report the case of a patient in whom the complete regression of the metaplasia was observed after medical therapy.
Subject(s)
Barrett Esophagus/drug therapy , Anti-Ulcer Agents/administration & dosage , Barrett Esophagus/pathology , Biopsy , Drug Therapy, Combination , Esophagus/pathology , Humans , Male , Middle Aged , Ranitidine/administration & dosage , Sucralfate/administration & dosageABSTRACT
Liver and spleen are the organs most frequently involved in the blunt abdominal trauma. Prognosis is severe in those cases classified as IV or V according to the More score. The imaging techniques, particularly CT scan, offer today a possibility in the nonoperative management of a selected group of haemodynamically stable patients, therefore reducing the need of surgery. The authors' experience in 125 patients observed from 1983 to 1991 is reported.
Subject(s)
Liver/injuries , Emergencies , Humans , Italy/epidemiology , Multiple Trauma/epidemiology , Multiple Trauma/mortality , Multiple Trauma/surgery , Postoperative Complications/epidemiology , Postoperative Complications/mortality , Rupture , Wounds, Nonpenetrating/epidemiology , Wounds, Nonpenetrating/mortality , Wounds, Nonpenetrating/surgery , Wounds, Penetrating/epidemiology , Wounds, Penetrating/mortality , Wounds, Penetrating/surgeryABSTRACT
A controlled study was carried out on 60 patients undergoing laparotomy to assess the role of a thymic factor (TP-1 Serono) in the prevention of postoperative infections. All patients entering the study were preoperatively shown to be at risk of sepsis on the basis of the response to skin multitest system for assay of delayed hypersensitivity (Multitest C.M.I. System). The patients were also postoperatively monitored with the same system. The lower incidence of infections in patients treated with the thymic factor with respect to untreated patients (p less than 0.05) and the postoperative response to skin tests have confirmed the efficacy of the thymic factor under study in the prevention of postoperative infections.
