[Detection of the human papillomavirus in hyperplastic and cancerous prostatic tissue with PCR]. / Ricerca di papillomavirus umani nel tessuto prostatico iperplastico e canceroso mediante PCR.

Human papillomavirus (HPV) infections are frequently associated with benign, pre-malignant and malignant lesions of the female genital region and male anogenital tract. Recently several studies have been performed to evaluate the presence of HPV in the adenomatous and carcinomatous prostatic tissue for the epidemiological implications due to the sexual transmission, and for the possible etiologic role in the development of prostatic carcinoma, first cause of death from neoplasia in men over 60 years in the developed countries. The role of HPV is still controversial since some authors evidenced the virus in prostatic tissue others did not detect its presence. We investigate the presence of HPV in 60 prostatic benign hyperplasias and in 5 prostatic carcinomas in surgically resected prostates by PCR technique using consensus and type specific primers. The analyzed specimens were negative for HPV DNA, although appropriate amplimers were present for beta-globin and positive controls. We therefore conclude that HPV infections are not commonly found in the human prostate.

Metastatic tumor of the spermatic cord from a primary silent colorectal adenocarcinoma.

Tumors of the spermatic cord are indeed rare and 91% are of mesenchymal origin. Nearly all epithelial tumors are metastases with the primary tumor located in the gastrointestinal tract, prostate, kidney. In 9.5% of cases, initial symptoms are localized to the metastatic site prior to the discovery of the primary tumor. When a diagnosis of epithelial malignant tumor of the spermatic cord is made an investigation for the primary site must be performed. We report a case of metastatic tumor of the right spermatic cord occurring as first clinical manifestation of a silent adenocarcinoma of the sigmoid colon.

Paraffinoma of the penis: one-stage repair.

OBJECTIVE: We report a rare case of paraffinoma of penis. A one-stage surgical treatment achieved optimal aesthetic and functional results. METHODS: We evaluated a 32-year-old man who self injected paraffin into his penis to facilitate erection and increase potency. After two months of paraffin oil injection, sclerosis and retraction produced a deformity of the penis with erectile dysfunction. Complete removal of the compromised skin and subcutaneous tissue was performed and, simultaneously, a pedicled scrotal flap was accurately prepared, directly turned up and wrapped around the penile shaft with interrupted 3-0 silk sutures. The scrotal incision was then closed. RESULTS AND CONCLUSION: Treatment by excision of granulomatous tissue and plastic reconstruction in a one-stage procedure, as also reported in the literature, is the only treatment that is able to achieve an effective result, both cosmetically and functionally. Excellent aesthetic and functional results were found at 34-months follow-up.

Myelolipoma of the adrenal gland presenting with dyspepsia and epigastric pain.

Myelolipomas are rare benign neoplasms of the adrenal glands, characterized by the presence of adipose tissue and elements of bone marrow in various degrees of differentiation. Usually asymptomatic, they are discovered incidentally or at autopsy; sometimes larger masses may cause local symptoms. We report clinical, radiologic and therapeutic aspects of a large myelolipoma of the right adrenal gland, presenting with unusual epigastric symptoms.

[Simultaneous enucleo-resection of synchronous bilateral renal carcinoma, incidentally discovered during prostate disease screening]. / Enucleoresezione contemporanea di carcinoma renale bilaterale sincrono, scoperto incidentalmente nel corso di uno screening per le malattie della prostata.

Bilateral synchronous renal cell carcinoma is rare, incidental discovery is exceptional. We report a case of asymptomatic bilateral simultaneous renal tumor discovered during screening for prostatic disease. Two year previously the patient underwent sonography and IVP for right ureteral stone, spontaneously ejected, with no evidence of renal masses. Ultrasound, CT and selective digital angiography demonstrated two renal tumors < 3 cm in size. Bilateral simultaneous enucleoresection was the therapeutic choice, that we consider to be elective in such a case.

Artificial spermatocele inserted onto the vas deferens: a clinical report.

This procedure was devised in an attempt to treat azoospermia caused by severe vas obstruction. An artificial spermatocele is prepared by resection of the vas slightly distal to the epididymal-deferential ansa and anastomosing onto its proximal stump a piece of Dardik's prosthesis sealed at the far end. During the partner's ovulatory period the spermatocele fluid is aspirated, mixed with fertile donor seminal plasma and used for artificial insemination. To date 8 subjects have had the operation: spermatocele fluids of 4 contained some highly motile spermatozoa with normal ability to penetrate cervical mucus for some months. Spermatocele implantation onto the vas apparently has the following advantages: the anatomic and functional integrity of the epididymis is maintained, the storage function of the epididymal-deferential ansa is preserved, and the risk of spermatocele collapse seems to be reduced by the high "vis a tergo" developed during ejaculation.