[Pathomorphological and morphometric evaluation of a model of aortic insufficiency in rabbits treated with taurine]. / Patomorfologicheskaia i morfometricheskaia otsenka modeli aortal'noi nedostatochnosti u krolikov pri lechenii taurinom.

In 45 experimental rabbits, subjected to trans-carotid aorto-valvulotomy in a month developed a congestive heart failure. When this group of rabbits was compared to the control group of 20 animals, in the course of complete pathomorphologic, histochemical and stereomorphologic analysis the following results were obtained: potassium oroticum did not show any efficacy at all; the efficacy of taurine in a dose of 10 mg/kg was low. Its effect was both direct and indirect acting through the autonomic nervous system.

[Effect of the carcinogenic tyrosine metabolite p-hydroxyphenyllactic acid on the ascorbic acid concentration in the organs and blood of mice]. / Vliianie kantserogennogo metabolita tirozina p-oksifenilmolochnoi kisloty na kontsentratsiiu askorbinovoi kisloty v organakh i krovi myshei.

The effect of cancerogenic tyrosine metabolite, p-hydroxyphenyllactic acid, on the concentration of ascorbic acid in the organs and blood of mice has been studied. p-Hydroxyphenyllactic acid was demonstrated to decrease considerably ascorbic acid concentration in the liver, adrenal glands and blood of mice. The above phenomenon and the previous data on tyrosine aminotransferase induction by p-hydroxyphenyllactic acid suggest the existence of two interdependent mechanisms of cancerogenic tyrosine metabolite (p-hydroxyphenyllactic acid) accumulation.