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1.
Acta Otorhinolaryngol Ital ; 32(5): 326-8, 2012 Oct.
Article in English | MEDLINE | ID: mdl-23326013

ABSTRACT

The aim of this study is to assess the use of a telescope with a high definition endoscopic video system as an alternative to the operating microscope in endoscopic laryngeal surgery. The system is economic, and allows optimal vision and improved surgeon comfort and ease. In exolaryngoscopy, the optic vitom is positioned in place of the microscope. An extracorporeal optical system (exoscope) is positioned 25 cm from the surgical field. Under exoscopic control, it is possible to use the same series of instruments using a long handle through the laryngoscope. The CO2 laser may also be used by fixing it coaxially to the optical system, and it is possible to use a classic set of microinstruments for phonosurgery. Endoscopic study with auto-fluorescence (NBI; narrow band imaging) can be easily used to visualize both precancerous and cancerous lesions. We treated 12 patients with benign and malign pathologies of the vocal cords; in all cases, the predicted result was reached, and the optic vitom showed its potential advantages in ease and comfort of the surgeon.


Subject(s)
Laryngeal Diseases/surgery , Laryngoscopy/instrumentation , Laryngoscopy/methods , Vocal Cords/surgery , Humans , Video-Assisted Surgery
3.
Drugs Exp Clin Res ; 11(7): 453-6, 1985.
Article in English | MEDLINE | ID: mdl-3836868

ABSTRACT

Levels of cefatrizine, a new oral cephalosporin, were determined in blood and in tonsils, paranasal sinus secretions and middle ear exudates from 18 patients with acute infections at these sites. Three and six hours after administration of 500 mg cefatrizine satisfactory levels of the antibiotic were found at all the sites examined. Levels in the tonsils and middle ear were higher than those in blood, while lower levels were recorded in nasal secretions.


Subject(s)
Cefatrizine/metabolism , Cephalosporins/metabolism , Ear, Middle/metabolism , Palatine Tonsil/metabolism , Paranasal Sinuses/metabolism , Bacterial Infections/drug therapy , Bacterial Infections/metabolism , Cefatrizine/blood , Cefatrizine/therapeutic use , Humans , Kinetics
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