ABSTRACT
Once the experience of GISSI I was concluded, the as yet unresolved problem of the choice of one fibrinolytic agent in preference to others emerged. In the present study, the authors used echocardiography in order to compare streptokinase with r-TPA in order to limit myocardial damage in acute myocardial infarction in 33 patients, average age 64.6 years. No statistically significant difference between the two drugs was observed as far as left ventricular contractility and extent of the infarcted region was concerned. This was in accordance with the findings of the Italian PAIMS study.
Subject(s)
Echocardiography , Myocardial Infarction/drug therapy , Streptokinase/therapeutic use , Thrombolytic Therapy , Tissue Plasminogen Activator/therapeutic use , Humans , Middle Aged , Myocardial Infarction/diagnostic imaging , Myocardial Infarction/physiopathology , Recombinant Proteins/therapeutic use , Ventricular Function, Left/drug effectsABSTRACT
Hyperkinetic ventricular arrhythmia being the main cause of electrical destabilization and hence fatal tachy-arrhythmias, we have studied, by Holter test, the prevalence of these arrhythmias in ambulatory non-professional athletes and compared it with a homogeneous group of sedentary subjects in order to evaluate if sports, even if not in athletic competitions, represent a potential risk for sudden death. The results show the prevalence of hyperkinetic ventricular arrhythmias to be similar in the two groups and not related to sports.
Subject(s)
Arrhythmias, Cardiac/epidemiology , Sports , Adolescent , Adult , Arrhythmias, Cardiac/diagnosis , Death, Sudden/etiology , Electrocardiography, Ambulatory , Female , Humans , Male , Physical Exertion , Risk FactorsSubject(s)
Myocardial Infarction/drug therapy , Thrombolytic Therapy , Adult , Aged , Aged, 80 and over , Clinical Enzyme Tests , Electrocardiography , Female , Follow-Up Studies , Humans , Male , Middle Aged , Myocardial Infarction/diagnosis , Streptokinase/therapeutic use , Time Factors , Tissue Plasminogen Activator/therapeutic use , Urokinase-Type Plasminogen Activator/therapeutic useABSTRACT
The authors evaluate old patients of both sexes with acute myocardial infarction. They study coronary risk factors, symptomatology onset, infarction site, complications and survival in Intensive Care Unit. The elderly women show significant features in comparison with the male as the particular predictive value of diabetes and hypertension and the greater atypia of clinical findings. The unforeseeable development of coronary artery disease in the female is confirmed also in the elderly.
Subject(s)
Myocardial Infarction/mortality , Aged , Aged, 80 and over , Diabetes Complications , Female , Humans , Hypertension/complications , Hypertriglyceridemia/complications , Italy/epidemiology , Male , Myocardial Infarction/blood , Myocardial Infarction/complications , Risk Factors , Sex FactorsABSTRACT
Acute myocardial infarction in the elderly shows epidemiological and clinical features different from those observed in the same pathology in the young-adult subject. In this study, the authors compare literature data with their experience of 309 subjects aged greater than or equal to 65 years vs. 268 controls. All these patients were hospitalized for acute myocardial infarction in an Intensive Care Unit. Risk factors, symptomatology at onset, lesion site and survival in the Intensive Care Unit were examined. Our study establishes that cardiologists need special diagnostic accuracy to evaluate coronary artery disease in old patients.