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Orv Hetil ; 155(17): 659-68, 2014 Apr 27.
Article in Hungarian | MEDLINE | ID: mdl-24755448

ABSTRACT

INTRODUCTION: Vitamin D deficiency is an important risk factor for fractures. However, there are few data available only on the relationship between serum 25-hydroxyvitamin D levels and recovery after surgery for hip fracture. AIM: The authors investigate the vitamin D supply of patients with hip fractures. METHOD: Between February and September 2013, serum 25-hydroxyvitamin D and parathyroid hormone levels were determined in 203 patients with hip fracture (74.8±11.5 ys; 67 men and 136 women) and in 74 control subjects. RESULTS: Vitamin D deficiency and secondary hyperparathyroidism occurred significantly more frequently in patients with hip fracture than in control subjects (72% vs. 45%, and 33% vs. 17%, respectively). Patients with better condition after surgery showed higher 25-hydroxyvitamin D levels (p<0.001) than those with poor condition. Serum 25-hydroxyvitamin D were lower in the 31 patients who died [median of survival time: 19 (5-52) days] compared to those who survived [22.6 (9.5-45.0) vs. 33.0 (16.5-56.6) nmol/l]. CONCLUSIONS: The association between vitamin-D deficiency and mortality as well as the positive correlation between serum 25-hydroxyvitamin D levels and better postoperative condition confirm the importance of proper vitamin D supply in the prevention and cure of hip fractures, what is more in the increase of the chance of survival.


Subject(s)
Hip Fractures/blood , Hip Fractures/etiology , Parathyroid Hormone/blood , Vitamin D Deficiency/blood , Vitamin D Deficiency/complications , Vitamin D/analogs & derivatives , Aged , Aged, 80 and over , Chronic Disease , Comorbidity , Female , Femoral Neck Fractures/blood , Femoral Neck Fractures/etiology , Hip Fractures/epidemiology , Hip Fractures/mortality , Hip Fractures/prevention & control , Humans , Hungary/epidemiology , Hyperparathyroidism, Secondary/blood , Hyperparathyroidism, Secondary/complications , Life Style , Male , Risk Factors , Seasons , Survival Analysis , Vitamin D/administration & dosage , Vitamin D/blood , Vitamin D Deficiency/drug therapy
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