ABSTRACT
OBJECTIVE: Thyroid disease is the second most commonly affected disease in childbearing women, after diabetes, and thyroid autoimmunity in pregnancy has been connected with adverse pregnancy outcomes such as miscarriage, recurrent miscarriage, preterm birth, and low IQ. The study seeks to determine the correlation between anti-thyroid peroxidase antibodies and unexplained recurrent miscarriage. PATIENTS AND METHODS: 124 women were included in this case-control study, divided into 62 women who have experienced unexplained recurrent miscarriages and 62 healthy women without a history of miscarriage. Screening for TSH and anti-TPO antibody were done for both groups. RESULTS: The prevalence rate of positive anti-TPO antibody in women with recurrent miscarriage was 19.4%, while in women without miscarriage was 6.5% (which is considerably higher in cases than in women without recurrent miscarriage with a p-value of 0.03 and an odd ratio of 3.48 (95% CI; 1.06-11.48). CONCLUSIONS: A statistically significant relationship between anti-TPO antibodies and recurrent miscarriage has been detected. We recommend screening for TSH and thyroid antibodies for women with recurrent miscarriages and further studies on the effect of levothyroxine therapy for euthyroid women with antibody positive.
Subject(s)
Abortion, Habitual , Premature Birth , Pregnancy , Female , Infant, Newborn , Humans , Case-Control Studies , Autoantibodies , Thyrotropin , PeroxidasesSubject(s)
Abdominal Fat/pathology , Adiposity , Cesarean Section , Pregnancy Complications/physiopathology , Waist Circumference , Adult , Body Composition , Body Mass Index , Emergency Service, Hospital , Female , Humans , Obesity/pathology , Obesity/physiopathology , Pregnancy , Pregnancy Complications/pathology , Pregnancy Trimester, First , Prospective Studies , Risk , Young AdultABSTRACT
The issue of maternal obesity has become a major public health problem. Internationally, the diagnosis of obesity is based on body mass index (BMI) that is, weight in kg/height in m2. While epidemiological associations have been shown between different BMI categories and adverse clinical outcomes, there is also a growing realisation that BMI has significant limitations. In this review, we assess current methods to measure body fat and, in particular, their application in pregnant women.
Subject(s)
Adiposity , Anthropometry/methods , Body Composition , Obesity/classification , Adiposity/physiology , Body Composition/physiology , Body Height/physiology , Body Mass Index , Body Weight/physiology , Densitometry , Electric Impedance , Female , Humans , Obesity/diagnosis , Obesity/epidemiology , PregnancyABSTRACT
Two sleep clinics run by health visitors were set up in Dundee to provide a brief, time-limited programme of advice and treatment for adults with insomnia and referred by their GPs. This article describes the clinics and reports the clinical features and outcome of the first 100 patients referred.
Subject(s)
Community Health Centers/organization & administration , Community Health Nursing/organization & administration , Sleep Initiation and Maintenance Disorders/nursing , Adolescent , Adult , Aged , Algorithms , Decision Trees , Humans , Middle Aged , Nursing Evaluation Research , Patient Education as Topic/organization & administration , Program Evaluation , Referral and Consultation , Sleep Initiation and Maintenance Disorders/diagnosis , Sleep Initiation and Maintenance Disorders/prevention & controlABSTRACT
The five freshman congressmen we're profiling in this issue have a lot more going for them than Mr. Smith did; most importantly, all bring strong community health and welfare concerns to Capitol Hill. A look at representatives of a sometimes surprising new crop of citizen-lawmakers.
