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1.
Curr Probl Cardiol ; 48(7): 101695, 2023 Jul.
Article in English | MEDLINE | ID: mdl-36921650

ABSTRACT

Transcatheter aortic valve replacement (TAVR) procedures have increased since adoption in 2010. Readmission for TAVR patients with underlying chronic congestive heart failure (cCHF) remains challenging. Therefore, we sought to determine the 30-day readmission rate (30-DRr) of patients who undergo TAVR & co-existing cCHF and its impact on mortality & healthcare utilization in the United States. We performed a retrospective study using the national readmission database year 2017 and 2018. The patients studied were discharged with TAVR as a principal diagnosis and underlying cCHF as a secondary diagnosis according to ICD-10 codes. The primary outcome was a 30-day readmission rate and mortality, while secondary outcomes were the most common diagnoses for readmission, and resource utilization. A total of 76,892 index hospitalization for TAVR with coexisting cCHF: mean age was 79.7 years [SD: ± 2], and 54.5% of patients were males. In-hospital mortality rate for index admission was 1.63%. The 30-DRr was 9.5%. Among the group of readmitted patients, in-hospital mortality rate was 3.13%. Readmission mortality showed a statistically significant increase compared to index mortality (3.13% vs 1.63%, adjusted P ≤ 0.001, aOR: 2.1, 95% CI: 1.6-2.9). The total healthcare in-hospital economic spending was $94.4 million, and total patient charge of $412 million. Approximately 1 in 10 patients who underwent TAVR with underlying cCHF had 30-DRr, with subsequent readmissions associated with increased healthcare spending. Readmission mortality showed a statistically significant increase when compared to index mortality. TAVR patients with cCHF are a vulnerable subset requiring additional outpatient care.


Subject(s)
Aortic Valve Stenosis , Heart Failure , Hemorrhagic Fever Virus, Crimean-Congo , Hemorrhagic Fever, Crimean , Transcatheter Aortic Valve Replacement , Male , Humans , United States/epidemiology , Aged , Female , Transcatheter Aortic Valve Replacement/adverse effects , Patient Readmission , Aortic Valve Stenosis/complications , Aortic Valve Stenosis/surgery , Aortic Valve Stenosis/diagnosis , Retrospective Studies , Hemorrhagic Fever, Crimean/complications , Hemorrhagic Fever, Crimean/surgery , Heart Failure/epidemiology , Heart Failure/therapy , Heart Failure/complications , Treatment Outcome , Risk Factors , Aortic Valve/surgery
2.
Curr Probl Cardiol ; 48(3): 101534, 2023 Mar.
Article in English | MEDLINE | ID: mdl-36481393

ABSTRACT

Venous vascular diseases are an important clinical entity estimated to affect several million people worldwide. Deep vein thrombosis (DVT) is a common venous disease with a population variable prevalence of 122 to 160 persons per 100,000 per year, whereas pulmonary embolism (PE) affects up to 60 to 70 per 100 000 and carries much higher mortality. Chronic venous diseases, which cause symptoms like leg swelling, heaviness, pain, and discomfort, are most prevalent in the elderly and significantly impact their quality of life. Some estimate that chronic vascular diseases account for up to 2% of healthcare budgets in Western countries. Treating venous vascular disease includes using systemic anticoagulation and interventional therapies in some patient subsets. In this comprehensive review, we discuss endovascular treatment modalities in the management of venous vascular diseases.


Subject(s)
Pulmonary Embolism , Venous Thrombosis , Humans , Aged , Venous Thrombosis/epidemiology , Venous Thrombosis/etiology , Venous Thrombosis/therapy , Quality of Life , Pulmonary Embolism/therapy , Pulmonary Embolism/drug therapy , Thrombolytic Therapy , Anticoagulants/therapeutic use , Risk Factors
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