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1.
Rev. Finlay ; 6(1-2): 55-62, 1992. tab
Article in Spanish | CUMED | ID: cum-17203

ABSTRACT

Se estudiaron 100 recien nacidos vivos del Hospital Provincial Ginecobstétrico de Cienfuegos que presentaron hipoxia perinatal severa a fin de determinar si en ellos se producían modificaciones morfométricas durante el primer año de vida. Al nacimiento pudo constatarse que el peso y las principales medidas antropométricas de estos niños tienden a ser evidentemente inferiores a las de los neonatos sanos. Posteriormente se aprecia que esos parámetros se acercan a las cifras del percentil 50 y al arribar al primer añode vida, se diferencian poco de los correspondientesa la población que no presentó afectaciones al nacer (AU)


Subject(s)
Asphyxia Neonatorum , Anthropometry , Infant
2.
Rev. Finlay ; 6(1/2): 55-62, 1992. tab
Article in Spanish | LILACS | ID: lil-267462

ABSTRACT

Se estudiaron 100 recien nacidos vivos del Hospital Provincial Ginecobstétrico de Cienfuegos que presentaron hipoxia perinatal severa a fin de determinar si en ellos se producían modificaciones morfométricas durante el primer año de vida. Al nacimiento pudo constatarse que el peso y las principales medidas antropométricas de estos niños tienden a ser evidentemente inferiores a las de los neonatos sanos. Posteriormente se aprecia que esos parámetros se acercan a las cifras del percentil 50 y al arribar al primer añode vida, se diferencian poco de los correspondientesa la población que no presentó afectaciones al nacer


Subject(s)
Anthropometry , Asphyxia Neonatorum , Infant
3.
Rev. Finlay ; 4(2): 55-60, abr.- jun. 1990. tab
Article in Spanish | LILACS | ID: lil-246140

ABSTRACT

Se estudia una muestra de 790 niños del municipio de Santa Clara cuyas edades oscilan entre los 5 y 13 años con el objetivo de evaluar el desarrollo dental de los mismos y su relación con el desarrollo físico general. Se considera además sexo y raza.Se demuestra el estado satisfactorio de la edad dental promedio y el índice de Rohrer como indicadores de las condiciones biológicas del individuo,así como la relación entre la edad dental retardada y la convivencia en condiciones socioeconómicas desfavorables que se hace muy evidente en el grupo de 10 años


Subject(s)
Tooth Eruption
4.
Fundam Appl Toxicol ; 11(1): 155-68, 1988 Jul.
Article in English | MEDLINE | ID: mdl-2905311

ABSTRACT

Chronic exposure to organophosphates (OP) can result in nonspecific neurologic signs in both man and animals. Improved methods are needed to predict toxicity and to better characterize neuromuscular effects. In this study, dogs were exposed to an OP (fenthion) by weekly dermal application of a 20% solution at a dosage of 44 mg/kg. This dosage does not produce signs of acute OP toxicity in dogs, although plasma cholinesterase (ChE) levels are significantly decreased. Electromyograms (EMG) were used to monitor motor unit potential (MUP) activity at minimal and submaximal contractile effort in four different muscles. At 1-month intervals, muscle biopsies were obtained and plasma ChE levels were determined. At 3 months, hyperreflexia and/or mild proprioceptive deficits were observed. The dosage was reduced to 22 mg/kg for the remaining 3 months of the study. At the end of this 6-month study, nerve and muscle biopsies were obtained. Mean plasma ChE levels were decreased (preexposure value of 1775 IU/liter to low of 310 IU/liter) and correlated with duration of exposure and change in dosage level. Fourier analysis of EMG indicated some increase in higher frequency components of the power spectrum with time, and analysis of individual MUPs revealed a significant (p less than 0.05) increase in the product of the amplitude times the duration of the potentials in all muscles examined. Biopsy results were supportive of EMG findings of altered neuromuscular function and loss of small motor units. The EMG changes were most consistent in the gastrocnemius muscle and were detected prior to development of clinical signs. These results indicate that EMG can be useful in monitoring OP exposure and predicting toxicity.


Subject(s)
Electromyography , Fenthion/toxicity , Muscular Diseases/chemically induced , Nervous System Diseases/chemically induced , Animals , Ataxia/physiopathology , Biogenic Amines/metabolism , Butyrylcholinesterase/metabolism , Carboxylic Ester Hydrolases/toxicity , Dogs , Female , Histocytochemistry , Leukocyte Count/drug effects , Muscles/metabolism , Muscles/pathology , Muscular Diseases/physiopathology , Nervous System Diseases/physiopathology , Neurotransmitter Agents/metabolism , Predictive Value of Tests
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