1.
Thromb Res
; 53(5): 435-45, 1989 Mar 01.
Article
in English
| MEDLINE
| ID: mdl-2734728
ABSTRACT
Many evidences indicate that heparin is an activator of fibrinolysis, but the most important side effect of heparin is bleeding which is a problem particularly in the high risk patient. Here we describe how chemical modifications, associated with separation techniques, can sharply reduce the anticoagulant activities of a heparin while its ability to stimulate fibrinolysis is retained.
Subject(s)
Fibrinolytic Agents , Heparin/pharmacology , Animals , Anticoagulants , Heparin/isolation & purification , In Vitro Techniques , Male , Molecular Weight , Oxidation-Reduction , Rabbits , Rats , Sheep , Swine , Uronic Acids/analysis
2.
Boll Soc Ital Biol Sper
; 49(22): 1316-21, 1973 Nov 30.
Article
in Italian
| MEDLINE
| ID: mdl-4807619
Subject(s)
Catalase , Liver/enzymology , Peptide Hydrolases , Animals , Catalase/analysis , Catalase/isolation & purification , Chymotrypsin , Horses , Papain , Peroxidases/analysis , Trypsin
3.
Boll Chim Farm
; 107(11): 697-710, 1968 Nov.
Article
in English
| MEDLINE
| ID: mdl-4239690
4.
Boll Chim Farm
; 107(11): 711-5, 1968 Nov.
Article
in Italian
| MEDLINE
| ID: mdl-5729797