ABSTRACT
Syncope - one of the most common syndrome in the general population - may be a manifestation of diseases associated with risk of sudden death. OBJECTIVE: To evaluate the prevalence, pathogenesis particular syncope, near syncope in children involved in elite sport. MATERIAL AND METHODS: The study involved 500 young elite athletes aged 9-18 years (mean age 16.1+/-2.2 years), member of Russian national teams.
Subject(s)
Athletes , Syncope , Adolescent , Child , Humans , Prevalence , Russia , SportsABSTRACT
UNLABELLED: Microvolt T-wave alternans (MTA) is one of markers of electrical myocardial instability. STUDY AIM: To elucidate normal range of MTA parameters during bicycle exercise test (ET) in adolescent elite athletes. MATERIAL AND METHODS: We examined 500 athletes aged 9-18 (mean 16.1 ± 2.2) years members of national teams of 27 kinds of sport. There were 333 females with mean age 16.0 ± 1.01 years and 167 males with mean age 16.3 ± 1.4. All athletes underwent ECG registration in clino- and ortho- positions and bicycle ET with automatic analysis of MTAT-wave alternans. RESULTS: Mean MTA value was 26 ± 13 (9-51) mV. MTA above 65 mV was registered in 10 persons (2.1%) 5 of whom had signs of overtraining. Sensitivity (Se) of MTA for detection of overtraining state was 21%, specificity (Sp)--99%, positive and negative predictive value--50 and 96%, respectively. CONCLUSION: Normal MTA range during ET is 9-51 mV. MTA values during ET do not depend on age and sex but are determined by duration of participation in sports and myocardial mass. MTA value is related to length of QT-interval. Increase of maximal MTA values above 65 mV is insensitive (Se 21%) but highly specific (Sp 99%) sign of overtraining in adolescent elite athletes.
Subject(s)
Arrhythmias, Cardiac/physiopathology , Athletes , Electrocardiography , Adolescent , Arrhythmias, Cardiac/diagnosis , Child , Exercise Test , Female , Humans , Male , Predictive Value of Tests , Reference ValuesABSTRACT
Microvolt T-wave alternans (MTA) is one of markers of electrical myocardial instability. STUDY AIM: to elucidate normal range of MTA parameters during bicycle exercise test (ET) in adolescent elite athletes. MATERIAL AND METHODS: We examined 500 athletes aged 9-18 (mean 16.1+/-2.2) years members of national teams of 27 kinds of sport. There were 333 females with mean age 16.0+/-1.01 years and 167 males with mean age 16.3+/-1.4. All athletes underwent ECG registration in clino- and ortho- positions and bicycle ET with automatic analysis.
ABSTRACT
A case of a rare disease - Andersen-Tawil the syndrome (ATS) is presented. Diagnosis of ATS, 7-th molecular-genetic variant of long QT syndrome was made basing on the characteristic clinical picture (periodic stress induced syncopal states), data of ECG and its Holter monitoring (pronounced QT prolongation, bouts of polymorphic bidirectional ventricular tachycardia), typical dysmorphic features (low-set ears, small mandible, brachydactyly, fifth-digit clinodactyly). However mutation of the KCNJ2 gene typical for this variant was not detected. Problems of pathogenesis, diagnostics, and treatment of the disease are discussed with special stress on class IC antiarrhythmic drugs.