ABSTRACT
Tests for hemocultures were performed in 51 patients with clinical diagnoses of sepsis treated in a reanimation unit. Microbial cultures were isolated from 30 patients (58.9 per cent). Staphylococci in pure cultures and associations were the causative agents of sepsis in 26 patients (86.4 per cent). The cultures of E. coli, Y. enterocolitica and Streptococcus faecalis were isolated from 2, 1 and 1 patients, respectively. Pus specimens from 111 patients with postinjection suppuration were tested and staphylococci in pure cultures and associations were detected in 90 patients (81.8 per cent). The cultures of P. vulgaris, Streptococcus pyogenes, E. coli, Str. faecalis, Enterobacter spp. and Pseudomonas aeruginosa were isolated from 10, 5, 3, 1, 1 and 1 patients, respectively. The results showed that Staphylococci played the leading role in development of the hospital infections. Treatment of such patients should be performed with an account of antibioticograms since many strains are resistant to various antibiotics.
Subject(s)
Abscess/etiology , Anti-Bacterial Agents/therapeutic use , Cross Infection/etiology , Staphylococcal Infections/etiology , Staphylococcus/pathogenicity , Surgical Wound Infection/etiology , Abscess/drug therapy , Abscess/microbiology , Cross Infection/drug therapy , Cross Infection/microbiology , Drug Resistance, Microbial , Humans , In Vitro Techniques , Staphylococcal Infections/drug therapy , Staphylococcal Infections/microbiology , Staphylococcus/drug effects , Surgical Wound Infection/drug therapy , Surgical Wound Infection/microbiology , Ukraine , Urban PopulationABSTRACT
The results of clinical observations on 34 patients with toxoplasmosis affecting mainly eyes over the period of 2-6 years are presented. The presence of antibodies to Toxoplasma, the content of IgA, IgM and IgG, as well as a number of characteristics of the T and B immunity systems in these patients were determined in their dynamics. For control, similar characteristics were determined in 28 practically healthy persons. During the period of observation the patients showed multiple fluctuations in the level of titers of serological reactions with toxoplasmic antigens and changes in the severity of the clinical picture. In contrast to healthy persons, toxoplasmosis patients were found to have statistically significant changes in a number of characteristics of the T immunity system. The content of B lymphocytes remained within normal limits. Complex treatment with the use of immunostimulating agents proved to be effective only in some of the patients.
Subject(s)
Toxoplasmosis, Ocular/immunology , Adjuvants, Immunologic/therapeutic use , Animals , Antibodies, Protozoan/analysis , Antibody Formation/drug effects , Chronic Disease , Coccidiostats/therapeutic use , Drug Therapy, Combination , Female , Humans , Immunity, Cellular/drug effects , Male , Recurrence , Toxoplasma/immunology , Toxoplasmosis, Ocular/drug therapyABSTRACT
Patients with sepsis have been found to have two types of alterations of central hemodynamics: hyperdynamic and hypodynamic ones, as well as alterations of the hepatic blood flow. The use of splenosorption results in normalization of the parameters of the central and hepatic hemodynamics. The positive hemodynamic effect of splenosorption seems to be associated with the increased nonspecific resistance as well as the activation of the endogenous mechanisms of defense.
