[The one-stage replacement of single anterior defects of the dental arches with endosseous implants using light-hardening filling materials]. / Odnomomentnoe zameshchenie odinochnykh frontal'nykh defektov zubnykh riadov éndoossal'nymi implantami s ispol'zovaniem svetootverzhdaiushchikh plombirovochnykh materialov.

Implantation with one-stage repair of a tooth crown using helioprogram has been conducted in 42 patients with single frontal defects of the teeth. A 2.5-3-year follow-up enables the conclusion on this method's safety, good functional and cosmetic results. Thus, it is worth introduction into wide practice.

[Bilateral exclusion of the duodenum in reconstructive surgery of the stomach]. / Dvustoronnee otkliuchenie dvenadtsatiperstnoi kishki v rekonstruktivnoi khirurgii zheludka.

The article analyses the results of modified gastric resection after Roux with bilateral exclusion of the duodenum in 13 patients with disease of an operated stomach. The operations were performed for peptic ulcer of the gastroenteroanastomosis in 5 patients, for biliary reflux gastritis in 3, and for reflux gastritis and coexistent Stages II-III dumping syndrome in 5 patients. The outcomes of treatment were studied in follow-up periods of up to 3 years. The results were good in 10 patients, satisfactory in 2, and poor in 1 patient. Recurrent peptic ulcers were not encountered. The clinical picture of biliary reflux gastritis was completely relieved in all of the 8 patients. The dumping syndrome phenomena were arrested in 2 patients and relieved significantly in another 2.

[Gastric motility and post-gastrectomy dumping syndrome]. / Motorika zheludka i postgastrorezektsionnyi demping-sindrom.

A direct relationship was revealed between disorders of gastric motility before the operation and the frequency and severity of the post-gastrectomy dumping syndrome in patients with peptic ulcer. The level of increase in the frequency and amplitude of the contractions and the basal tonus of the gastric stump may serve as an objective criterion for establishing the severity of the dumping syndrome. Patients with an initial hyperkinetic type of motility are predisposed to the dumping syndrome, which must be borne in mind in choosing a variant of the operation and the method for creating the gastrointestinal anastomosis.

[Metabolic aspects of readaptation after hypokinesia (based on experimental results with animals)]. / Metabolicheskie aspekty readaptatsii posle gipokinezii (po rezul'tatam éksperimentov na zhivotnykh).

This review discusses changes in protein, carbohydrate and lipid metabolism of animals during their readaptation after exposure to hypokinesia of varying duration. It is concluded that at an early stage of readaptation anabolic reactions aimed at the recovery of the bulk of active muscle proteins and the amount of energy substrates are predominant. In this situation the synthesis of lipids and carbohydrates is prevailing over their utilization. It is postulated that during readaptation amino acids are used more actively to make up for energy expenditures, gluconeogenesis and lipid synthesis. In the course of readaptation wave-like metabolic changes occur, being sometimes greater than during hypokinesia.

[DNA and RNA synthesis in isolated nuclei of rat skeletal muscle fibers following hypokinesia]. / Sintez DNK i RNK v izolirovannykh iadrakh volokon skeletnykh myshts krys pri gipokinezii.

Incorporation of labelled nucleotides [3H] UTP and [3] TTP revealed the intensity of DNA and RNA synthesis in the skeletal muscle nuclei in vitro in the male rats of Wistar line after 22-day immobilization. The RNA biosynthesis (the intensity of transcription) considerably diminished in the skeletal muscle nuclei of hypokinetic rats (by 1.8 times). No differences developed in the actinomycin D depression of r-RNA and s-RNA synthesis. The DNA biosynthesis (the intensity of replication) also decreased. The depression of DNA and RNA biosynthesis seems to be the main reason of the decreased intensity of protein synthesis in the rat skeletal muscle during hypodynamia.

[Motor activity and the prevention of the sequelae of hypokinesia (according to tissue metabolic indices)]. / Dvigatel'naia aktivnost' i profilaktika posledstvii gipokinezii (po pokazateliam tkanevogo obmena).

The content of protein, DNA and RNA was measured in rats that had been exposed to 90-day hypokinesia: hypokinesia alternating with unrestrained maintenance and hypokinesia combined with exercises (swimming). Adverse effects of hypokinesia on metabolism seemed to build up. Short-term passive rest was insufficient to make up deficiency in motor activity. The recovery of metabolic disorders after prolonged hypokinesia proceeded in a non-uniform and slow manner: most parameters did not return to the initial level within one month. During the first two weeks exercises produced effects similar to those of hypokinesia. By the 30th and 60th days they shower their normalizing effect on tissue metabolism. When developing work-rest cycles for the people who are exposed to partial hypokinesia during work and do exercises as a countermeasure against hypokinetic effects, biochemical analysis of blood (nonesterified fatty acids, acetone bodies, cholesterol, beta-lipoproteins, urea) and urine (potassium, calcium, creatinine) should be made to measure metabolic processes in tissues.

[Biochemical changes in skeletal muscles during hypokinesia and possible means for counteracting them]. / Biokhimicheskie izmeneniia v skeletnykh myshtsakh pri gipokinezii i vozmozhnye puti ikh vosstanovleniia

The changes in the metabolism of proteins, carbohydrates, fats, water and minerals as well as in the acitvity of enzymes of skeletal muscles during hypokinesia are discussed. The methods used to reverse metabolic disorders in skeletal muscles are recommended and evaluated. Among the suggested methods-the diet with predominant proteins, hypoxia, anabolic steroids and physical exercises-the latter seem to be most promising.