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Prikl Biokhim Mikrobiol
; 43(6): 685-90, 2007.
Article
in Russian
| MEDLINE
| ID: mdl-18173111
ABSTRACT
To impart antimicrobial activity to surgical sutures, weaved polyester fibers are coated with poly-3-hydroxybutyrate (PHB), containing the antimicrobial agent furazolidone (FZ). The prolonged FZ effect (7-14 days) is achieved by two-step application of a sheath, constituting 10% of the suture weight and containing 2-6% FZ. The sheath structure and antimicrobial activity of sutures can be modified by the introduction of other biocompatible and biodegradable polymers.