[Expert Council Resolution. Practical Aspects of the Diagnosis and Correction of Potassium and Magnesium Deficiency States].

The article analyzes properties of potassium and magnesium, which may exert vasodilatory, anti-inflammatory, anti-ischemic, antiaggregant, and antiarrhythmic effects. These are extremely important microelements and potentially beneficial therapeutic agents for treatment of cardiovascular diseases.

[Insulin-glucose parameters in healthy women and patients with arterial hypertension and ischemic heart disease in dependence on age and follicle-stimulating hormone levels].

Insulin-glucose parameters in healthy women do not significantly change with changes of functional state of ovaries. Women with hypertension and normal levels of glycemia have significantly higher values of basal insulinemia and HOMA-R index reflecting presence of moderate insulin resistance degree of which is more pronounced in middle aged patients. In women with documented ischemic heart disease values of basal insulinemia, HOMA-R index, and glycemia are comparable with those in patients with hypertension and follicle-stimulating hormone level above 30 IE/l and significantly differ from corresponding parameters in healthy women in peri- and postmenopause.

[Coronary atherosclerosis and total serum cholesterol in men and women].

The study shows that the extent of atherosclerotic changes in the coronary arteries, revealed during coronaroangiography, has a significant correlation with the serum level of total cholesterol (TC). In patients with normal (less than 5.2 mmol/ l) TC the number of involved arteries and the number of stenotic segments are significantly smaller than those in patients with a TC level higher than 6.5 mmol/l.

[Hormone-producing function of the ovaries in young and middle-aged women with arterial hypertension and coronary heart disease].

The study demonstrates that arterial hypertension itself, judging by main anthropometric variables such as body weight index and waist to hip ratio, together with the estrogen-producing function of the ovaries, evaluated by measuring follicle-stimulating hormone levels, contributes substantially to the forming of abdominal obesity in normo- and hypertensive women. All the above confirms close correlation between hemodynamic and metabolic disturbances which eventually result in coronary heart disease in young and middle-aged women.

[On the possible prooxidant role of insulinemia in formation of metabolic syndrome in men and women.]. / O vozmozhnoi prooksidantnoi roli insulinemii v formirovanii metabolicheskogo sindroma u muzhchin i zhenshchin.

Levels of basal insulinemia, malondialdehyde (an index of oxidative stress) and some metabolic parameters were studied in 143 men and 83 women aged 48.3+/-0.7 years with incomplete metabolic syndrome: hypertension, abdominal obesity, dyslipoproteinemia with normoglycemia. Basal insulinemia correlated significantly with malondialdehyde levels both in men and women. Slose relationship was also found between basal insulinemia and waist circumference.

[Myocardial infarction in women: risk factors and clinical features]. / Faktory riska i osobennosti techeniia infarkta miokarda u zhenshchin.

The course of myocardial infarction (MI) in women, especially 60 years of age and older, is characterized by such severe complications as cardiorrhexis, hypovolemic cardiogenic shock, asystole, recurrent ventricular fibrillation and electromechanic dissociation responsible for the majority of lethal outcomes. Especially high MI lethality is in women at the age 70-79 years who have also the highest incidence of recurrent macrofocal MI while small-focal MI occurs in women over 80 years of age (80-89) more frequently than in 60-year-olds and younger. Dominating MI risk factors in women were the following: arterial hypertension detected in 81% patients under 60 and 90.8% cases over 60 years; abnormal lipid spectrum of blood including hypercholesterolemia (HCE), hypertriglyceridemia (HTE) and low concentration of HDLP cholesterol. HCE and HTE closely correlated with abdominal obesity irrespectively of age. Early menopause in women under 60 and diabetes mellitus of type 2 in older women, accumulation of two and more factors of risk contribute to development of coronary heart disease and MI, in females.