[The new approaches to understanding of neurohumoral regulation in overweight and ways of its correction]. / Novye podkhody k ponimaniiu neirogumoral'noi reguliatsii pri izbytochnoi masse tela i sposoby ee korrektsii.

The clinical study reflex of food specific dynamic effect food SDE reflex phase in various forms of obesity permit differential diagnosing and choosing of special diet therapy with the use of various biologically active food supplements.

[Thermal skin reaction to food intake and its changes in certain forms of obesity]. / Temperaturnaia reaktsiia kozhi na priem pishchi i ee izmeneniia pri nekotorykh formakh ozhireniia.

The authors review data on recently discovered temperature response of deep skin layers to the meal. The reaction is of a reflex nature and is one of the mechanisms regulating heat exchange in the body. In healthy people this reaction is weak. In alimentary obesity, it becomes much stronger, probably due to impaired heat exchange because of accumulated fat. In obesity related to diencephalic syndrome skin reaction is similar to control. In this obesity, pituitory seems to lose ability to regulate circulation in the blood. The above reaction can be used as a test differentiating the two forms of obesity.

[Thermal reaction of subcutaneous tissue to food intake in patients with obesity]. / Termicheskaia reaktsiia podkozhnoi kletchatki na priem pishchi u bol'nykh ozhireniem.

Investigating the temperature of deep layers of skin and in the main of subcutaneous tissue in patients with obesity we found the close connection between changes of this temperature and food intake. In patients who are in postabsorptive period the intake of the small portion of test food (220 kcal) induces in 3-4 min a marked increase of the subcutaneous tissue temperature (often by 1.0-1.5 degrees C in comparison with the initial level). Further the temperature still rises some what and then keeps at increased level for 30-45 min. At the end of the treatment course of patients in the clinic (and the body weight loss by 10-14 kg) these changes of the temperature become much less intensive or do not quite manifest. The above thermic reaction is developed apparently as a result of the dilatation of blood vessels of the skin and filling the venous plexus with the arterial blood. Probably in depends upon the regulatory activity of hypothalamus which is directed on an increase of heat loss into environment.

[Excess body weight at a young age as a risk factor for developing metabolic diseases]. / Izbytochnaia massa tela v molodom vozraste - faktor riska razvitiia boleznei metabolisma.

A total of 100 patients, aged 16-25 years, suffering from metabolic-alimentary obesity were investigated under clinical conditions. An analysis was made of deviations from the normal parameters of arterial pressure, blood serum lipids, and other risk factors of the development of atherosclerosis, coronary heart disease, essential hypertension and other metabolic diseases. The shifts detected could be directly dependent of the disorders in nutrition. Alimentary correction of the disorders noted, reduction of body mass resulted in the improvement of the subjective conditions of patients, and in normalization of the above parameters. However, in some patients significant improvement in the metabolic status of the patients (lipid, in particular) was not achieved. The necessity of dispensary follow-up of young patients with obesity has been considered.