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1.
Aviakosm Ekolog Med ; 26(4): 35-9, 1992.
Article in Russian | MEDLINE | ID: mdl-1296836

ABSTRACT

The pre- and postflight biochemical analyses of the blood of 16 cosmonauts flown aboard Mir orbital station over 125-366 days revealed the changes in carbohydrate, lipid and protein metabolism being in line with the present-day ideas about the space flight effects on the human metabolism. A particular individual pattern of the responses and the absence of correlation with flight duration of space expeditions ranging from 4 months to a 1 year, are noted.


Subject(s)
Blood/metabolism , Space Flight , Energy Metabolism , Humans , Time Factors , USSR , Weightlessness
3.
Vopr Pitan ; (2): 39-43, 1986.
Article in Russian | MEDLINE | ID: mdl-3705542

ABSTRACT

The effect of diets containing soybean proteins substituting a significant portion of meat proteins was studied in patients with hyperlipidemia, type IIa, and in experiments on rats. It was found that soybean proteins included into the diet induced blood plasma amino acid imbalance, changed the excretion of some amino acids with urine, and significantly diminished the blood plasma cholesterol level. In the experiments on rats a reduced rate was noted in the low-density lipoprotein apoprotein formation and high-density lipoprotein apoprotein regeneration in the blood plasma. It is suggested that the hypocholesterolemic effect of soybean proteins is caused by decreased apoprotein E synthesis and metabolism due to low levels of blood plasma lysine and arginine.


Subject(s)
Anticholesteremic Agents , Dietary Proteins/therapeutic use , Glycine max , Plant Proteins/therapeutic use , Adult , Amino Acids/analysis , Animals , Apolipoproteins/blood , Cholesterol, HDL/blood , Cholesterol, LDL/blood , Coronary Disease/diet therapy , Coronary Disease/metabolism , Drug Evaluation , Drug Evaluation, Preclinical , Half-Life , Humans , Hyperlipoproteinemia Type II/diet therapy , Hyperlipoproteinemia Type II/metabolism , Male , Middle Aged , Rats , Rats, Inbred Strains
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