Subject(s)
Heartburn/etiology , Pregnancy Complications , Antacids/therapeutic use , Esophagogastric Junction/physiopathology , Female , Heartburn/drug therapy , Heartburn/physiopathology , Humans , Pregnancy , Pregnancy Complications/drug therapy , Pregnancy Complications/physiopathology , Progesterone/bloodABSTRACT
A review of 34, 201 multigravid deliveries found 47 patients who had severe pre-eclampsia after previous normotensive, non-albuminuric pregnancies. In 13 of these patients the affected pregnancy was apparently by a new father compared with 3 matched controls (P less than 0.01). This evidence supports the idea of a paternal immunogenetic factor in pre-eclampsia; immunogenetics.
Subject(s)
Paternity , Pre-Eclampsia/etiology , Adolescent , Adult , Female , Humans , Immunogenetics , PregnancySubject(s)
Eclampsia/genetics , Paternity , Pre-Eclampsia/genetics , Eclampsia/immunology , Female , Humans , Male , Pre-Eclampsia/immunology , PregnancySubject(s)
Labor, Induced , Prostaglandins E/administration & dosage , Adolescent , Adult , Female , Gels , Humans , Pregnancy , VaginaABSTRACT
We describe two patients with Nelson's syndrome in whom pregnancy progressed normally to spontaneous delivery of normal infants. One patient, who subsequently was found to have a basophil adenoma of the pituitary, developed diabetes insipidus in late pregnancy and the diabetes insipidus regressed spontaneously after delivery.
Subject(s)
Nelson Syndrome/complications , Pituitary Neoplasms/complications , Pregnancy Complications , Adult , Diabetes Insipidus/complications , Female , Humans , Pregnancy , Pregnancy in Diabetics/complicationsABSTRACT
The incidence of pre-eclampsia in 125 primigravidas who had previously received blood-transfusions was significantly less than in a matched series of controls--i.e., 12.8% compared with 23.2%. This suggests that immunological factors may be involved in the aetiology of pre-eclampsia.
