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1.
Appl Radiat Isot ; 169: 109568, 2021 Mar.
Article in English | MEDLINE | ID: mdl-33385758

ABSTRACT

Few places in the world produce iodine-125. In Brazil, the first production was achieved by using the IEA-R1 nuclear reactor located at Nuclear and Energy Research Institute - IPEN. To verify the quality of iodine-125 produced, and the amount of contaminants such as iodine-126, cesium-134 and caesium-137 among others, iodine-125 samples were immobilized into epoxy matrix disc, with the same geometry of a barium-133 reference radioactive source, used to calibrate an HPGe detector. The HPGe detector has a thin carbon composite window, which allows measure the iodine-125 photopeaks, between 27.1 and 35.4 keV. The method employed here was successful in producing and measurement of iodine-125.

2.
Appl Radiat Isot ; 165: 109307, 2020 Nov.
Article in English | MEDLINE | ID: mdl-32738753

ABSTRACT

In order to provide prostate brachytherapy treatment for more Brazilian men, IPEN is building a laboratory for the manufacture of radioactive sources. The new methodology for the production of iodine-125 seeds with yield 71.7% ± 5.3%. Points of importance were evaluated/discussed: photo-sensibility, reaction vial type, the substitution for iodine-131, pH, and solution volume. The surface was analyzed by FTIR and EDS. At the end, a Monte Carlo-MCNP6 simulation was performed to evaluate the TG-43 parameters.


Subject(s)
Iodine Radioisotopes/therapeutic use , Neoplasms/radiotherapy , Prostatic Neoplasms/radiotherapy , Brachytherapy/methods , Humans , Iodine Radioisotopes/administration & dosage , Male , Monte Carlo Method , Spectrometry, X-Ray Emission , Spectroscopy, Fourier Transform Infrared
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