Elements of renal injury in patients with varicose ulcer. Preliminary study.

The kidney may be affected in the processes of microbial, viral, parasitic infections. Knowledge of renal disease during chronic infection, with a different location than the throat, is of particular importance for the practicing physician for the detection and prevention of impaired renal function. Chronic kidney disease recovered in the early stages can prevent the progression of renal function decline. We studied a total of 85 patients with varicose ulcers with a mean age of 66.78 +/- 12.09 years, hospitalized in the Clinic of Dermatology and a control group consisting of 110 apparently healthy individuals. Urinary abnormalities have been detected in 26 (30%) of patients studied. GFR < 60 ml/min have been detected in 14 (17%) of patients studied. CRF stage II have been detected in 36 (42%) of patients studied. We detected recurrent varicose ulcer in 2 (2%) of patients studied. In two (2%) of patients during hospitalization we found a decrease in GFR by 15 and 12 ml/min, accompanied by an increase in serum creatinine from 0.7 mg % to 1 mg % in one patient and in another patient from 1.5 mg % to 2 mg %. Urinary abnormalities detected in patients with both acute and recurrent erysipelas warn about renal impairment and the need for monitoring of the renal patients with varicose ulcers.

Elements of renal injury in patients with erysipelas.

Erysipelas is an infectious disease caused by group A beta hemolytical streptococci which may produce renal lesions, most frequently glomerular disease. Renal injury although known is less studied in practice. Rarely bioptical exams have been performed, thus the problem of the relationship erysipelas glomerular disease is practically not solved. The aim of this study was a cross-sectional analysis of renal involvement produced by erysipelas in two departments where patients with erysipelas are diagnosed and treated: Dermatology and Infectious Diseases. We investigated 166 patients (86M, 80F; mean age 61.66 +/- 18.42) with erysipelas hospitalized in the Departments of Dermatology (55 patients-33%) and Infectious Diseases (111 patients-66%) during 2005-2009. The diagnosis was established on clinical and biological data. In these patients clinical and biological exam has been performed. We assessed GFR and urinalysis (hematuria and proteinuria). The control group consisted of 110 apparently healthy persons. Of the 166 patients with erysipelas we found asymptomatic urinary abnormalities in 82 (47%), isolated proteinuria in 19 (11%) patients and proteinuria associated with hematuria in 21 (13%) patients, and isolated hematuria in 38 (23%) patients. We did not find patients with nephrotic or nephritic syndrome. In the control group we found asymptomatic urinary abnormalities in 25 (23%) of the patients. A statistically significant difference was between the two groups (p < 0.01). Asymptomatic urinary abnormalities have been more frequent in patients with erysipelas from the Infectious Diseases Department compared to those from the Dermatology Department. A statistically significant difference has been found (p < 0.03). In patients with recurrent erysipelas (43 patients-26%) we found asymptomatic urinary abnormalities in 26 (54%) of the patients compared to the presence of asymptomatic urinary abnormalities in patients with acute erysipelas in 56 out of 123 (46%). Mean GFR in patients with erysipelas was of 73.94 +/- 27.79 ml/min. It was lower in patients with recurrent erysipelas, 72.13 +/- 24.74 mL/min respectively. Association of proteinuria with hematuria was more frequent in patients with recurrent erysipelas. Patients with asymptomatic urinary abnormalities during the course of erysipelas need to be closely monitored during antibiotic treatment.

Impetigo herpetiformis with postpartum flare-up: a case report.

Impetigo herpetiformis is a rare dermatosis of pregnancy with typical onset during the last trimester of pregnancy and rapid resolution during the postpartum period. It is still a matter of debate whether it is a variant of pustular psoriasis or a separate entity. We report a case of impetigo herpetiformis with an earlier onset during the second trimester of pregnancy (G4 P2) and an atypical postpartum flare-up. Even though the case is not new per se, it reveals the natural course of this rare disease because the condition was neglected and given no oral treatment throughout the entire pregnancy. Consequently, the patient had a premature delivery with premature rupture of membranes, placental insufficiency, and intrauterine growth retardation.

[Medical relationships between Moldavia and the Banat in the 19th and the 20th centuries]. / Relatii medicale Moldavo-Banatene în secolele XIX SI XX.

The intellectual and medical relationships between Moldavia and the Banat were established already in 1833. At that time, Damaschin Bojinca was appointed professor in Jassy, and he was followed by Eftimie Murgu. At the end of June 1833, "The Society of Physicians and Naturalists of Jassy" was founded. Among its founders, we can mention Dr. Iacob Christian Stanislaus Czihak, Dr. Mihail Zotta and Dr. Constantin Vârnav. Eftimie Murgu became a honorary member of this prestigious society. Among its corresponding members were dr. Pavel Vasici Ungureanu and the military medical doctor Friderich Abl from Timisoara. In the first decade after the great Union, the number of general practitioners in the Banat was higher than the number of Bucharest graduates. After the Faculty of Medicine was set up at the West University in Timisoara (by the Order in Council of 4 May 1945), a number of valuable physicians and teachers from Jassy contributed significantly to laying the basis of a high quality medical school in Timisoara.

[Trichothiodystrophy and hypereosinophilic syndrome, an unusual association]. / Trichothiodystrophie et syndrome d'hyperéosinophilie, une association insolite.

We present a case of trichothiodystrophy associated with a hypereosinophilic syndrome. This case had been followed for 30 years. Trichothiodystrophy was characterized by lamellar ichthyosis, hair and nail dystrophies, kyphoscoliosis, congenital luxation of the hip. The hypereosinophilic syndrome was characterized by an itching urticaria-like eruption. Although the patient's general condition had remaining stable for 30 years, during the last year it worsened and the patient suddenly died. The authors discuss about the significance of this association.

[Cat-scratch disease. Comments on a clinical case]. / Boala zgîrieturii de pisica. Consideratii în legatura cu un caz clinic.

The authors present a clinical case of cat's scratch disease, with lymphadenitis and inoculation pustule. A series of observations are made on the importance of anamnesis, histopathologic examination, elimination of other clinical entities with lymphadenopathic manifestations, for determining the diagnosis. The recent investigations are aimed at identifying the etiologic agent. The treatment of the disease is symptomatic.