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1.
Opt Lett ; 37(2): 190-2, 2012 Jan 15.
Article in English | MEDLINE | ID: mdl-22854463

ABSTRACT

Nanoscale rifts and ripples at a periodicity of 130 nm were generated on Si(100) surfaces immersed in water using tightly focused 800 nm 12 fs pulsed 85 MHz laser light at subnanojoule pulse energies. At radiant exposure close to the ablation threshold rifts were typically 20-50 nm in width and 70 nm in depth running perpendicular to the laser polarization. On increase of the irradiance, the rifts broadened and formed periodic ripples, whereas at highest exposure, a random nanoporous surface topology emerged. Rift and ripple formation is explained by laser-induced standing surface plasma waves, which result in periodic variation of dissipation and ablation.

2.
Opt Lett ; 37(4): 563-5, 2012 Feb 15.
Article in English | MEDLINE | ID: mdl-22344107

ABSTRACT

In magnetron sputtered indium-tin-oxide thin films of varying oxygen content, nanostructures were formed using tightly focused high-repetition rate near-infrared sub-15 femtosecond pulsed laser light. At radiant exposure well beyond the ablation threshold, cuts of 280-350 nm in width were generated. Illumination close to the ablation threshold resulted in periodic cuts of typically 20 nm in width at periodicities between 50 nm and 180 nm, as well as single sub-20 nm cuts. Subthreshold exposure, in combination with hydrochloric acid etching, yielded nanowires of 50 nm minimum lateral dimensions.

3.
J Neural Eng ; 5(1): 68-74, 2008 Mar.
Article in English | MEDLINE | ID: mdl-18310812

ABSTRACT

Organic field effect transistors can be integrated into micromachined polyimide-based neural stimulation electrode arrays in order to build active switching matrices. With this approach, a matrix of N x M electrode contacts requires only N + M interconnects to a stimulator when active switching elements are used instead of N x M interconnects. In this paper, we demonstrated that pentacene-based organic field effect transistors (OFETs) can be used to drive stimulation currents through neural electrodes in a physiological-like environment. In order to prove the general applicability as an implant material, the cytotoxicity of pentacene was evaluated with respect to potential effects on cell viability. The results of these tests indicate that extracts from pentacene inhibit neither proliferation nor metabolism of the tested mouse fibroblasts. However, some effect on cell spreading was observed when cells were in direct contact to pentacene for 48 h. In pilot experiments it was demonstrated for the very first time that pentacene transistors can be used as switching elements, acting as voltage-controlled current sources, capable of driving currents suitable for electrical stimulation of a peripheral nerve via a tripolar cuff electrode.


Subject(s)
Electric Stimulation/instrumentation , Electrodes, Implanted , Animals , Antimetabolites , Biocompatible Materials , Bromodeoxyuridine , Cell Survival/drug effects , Cells, Cultured , Electric Stimulation/adverse effects , Electrodes, Implanted/adverse effects , Equipment Design , Fibroblasts , Mice , Nanotechnology , Naphthacenes/chemistry , Naphthacenes/toxicity , Pilot Projects , Polymers/chemistry , Polymers/toxicity , Sciatic Nerve/physiology , Semiconductors/adverse effects , Xenopus laevis , Xylenes/chemistry , Xylenes/toxicity
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