ABSTRACT
<p><b>OBJECTIVE</b>The purpose of this study was to discuss the principle in neck treatment of cN0 patients with squamous cell carcinoma of buccal mucosa.</p><p><b>METHODS</b>101 patients of squamous cell carcinoma of buccal mucosa at the stage of cN0, who had hospitalized in West China College of Stomatology, Sichuan University from 1980 to 2000, were investigated retrospectively. All the patients received a comprehensive therapy consisting of surgical procedures combined with chemotherapy and radiotherapy. The combining radical therapy of buccal, mandible and neck was the main surgical method. Lymph nodes were cleared after operation and examined by pathological method. The patients had been followed up for more than 3 years.</p><p><b>RESULTS</b>17 patients had lymph nodes metastasis, the occult metastasis (OM) rate was 16.83%. It increased in the high stage of original lesion, the OM rate of T3 and T4 was 18.18% and 52.00%, respectively. The metastasized lymph nodes were mainly located in submandible and superior deep cervix lymph nodes, their respective metastasis rate was 41.18% and 29.41%.</p><p><b>CONCLUSION</b>The rate of occult metastasis of squamous cell carcinoma of buccal mucosa is high, and then we should adopt actively selective neck dissection for the cN0 patients of squamous cell carcinoma of buccal mucosa.</p>
Subject(s)
Female , Humans , Male , Middle Aged , Carcinoma, Squamous Cell , General Surgery , Lymphatic Metastasis , Mouth Mucosa , General Surgery , Mouth Neoplasms , General Surgery , Neck Dissection , Methods , Neoplasm Staging , Retrospective StudiesABSTRACT
<p><b>OBJECTIVE</b>To investigate the regularity of cervical lymph-node metastasis in oral squamous cell carcinoma patients and determine the treatment principle to cN0 patients.</p><p><b>METHODS</b>1,024 oral squamous cell carcinoma cases who underwent neck dissection between 1980-2001 were investigated retrospectively.</p><p><b>RESULTS</b>The total rate of cervical lymph-node metastasis of oral squamous cell carcinoma was 36.62% (375/1,024), the metastasis rate of cancer in tongue, buccal, gingival, and floor of mouth was 42.82%, 31.93%, 32.76%, and 25.00%, respectively; the rate of occult metastasis was 20.94%(71/339), the incidence of occult metastasis was closely related to the location of primary lesion and T stage.</p><p><b>CONCLUSION</b>The results in this study revealed that the therapy regime of the oral squamous cell carcinoma should be based on carefully clinical examination and compositive analysis on primary lesion related to size, location and cervical lymph-node.</p>
Subject(s)
Adolescent , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Carcinoma, Squamous Cell , Pathology , General Surgery , Lymphatic Metastasis , Mouth Neoplasms , Pathology , General Surgery , Neck Dissection , Neoplasm Staging , Retrospective Studies , Tongue Neoplasms , Pathology , General SurgeryABSTRACT
0.05). ALP activity of the cells on deproteinized bone was higher than that on decalcified bone(P
