ABSTRACT
No disponible
Subject(s)
Humans , Male , Female , Adult , Sweet Syndrome/diagnosis , Sweet Syndrome/immunology , Skin Diseases/complications , Skin Diseases/diagnosis , Skin Diseases/immunology , Autoimmunity , Autoimmunity/immunology , Lupus Erythematosus, Systemic/complications , Lupus Erythematosus, Systemic/diagnosis , Lupus Erythematosus, Systemic/immunology , Lupus Erythematosus, Cutaneous/complications , Adrenal Cortex Hormones/therapeutic use , Prednisone/therapeutic use , Immunosuppressive Agents/therapeutic use , Azathioprine/therapeutic useABSTRACT
No disponible
Subject(s)
Female , Humans , Male , Cyclosporine/administration & dosage , Cyclosporine/therapeutic use , Psoriasis/congenital , Psoriasis/pathology , Urticaria/diagnosis , Multicenter Studies as Topic/methods , Cyclosporine/metabolism , Cyclosporine/pharmacology , Psoriasis/prevention & control , Psoriasis/therapy , Urticaria/complications , Multicenter Studies as Topic , Prospective StudiesABSTRACT
Amyopathic dermatomyositis (ADM) is characterized clinically by typical skin lesions with hypomyopathy or no muscular involvement. ADM has been recently reported to be complicated by rapidly progressive interstitial lung disease (ILD), especially in patients with positive antibodies against melanoma differentiation-associated gene 5 (MDA5). These patients may have a low risk of cancer, but no clinical, histological or laboratory markers completely specific for paraneoplastic DM have been identified to date. We report a case of flagellate erythema as the initial presentation of ADM associated with ILD, positive MDA5 antibodies and a concomitant diagnosis of thyroid cancer. We discuss the unusual clinical features and associations that make this case particularly interesting.
Subject(s)
Autoantibodies/blood , DEAD-box RNA Helicases/blood , Dermatomyositis/pathology , Paraneoplastic Syndromes/pathology , Thyroid Neoplasms/complications , Dermatomyositis/immunology , Humans , Interferon-Induced Helicase, IFIH1 , Lung Diseases, Interstitial/diagnosis , Male , Middle Aged , Paraneoplastic Syndromes/immunologyABSTRACT
Presentamos una revisión actualizada en materia de avances en la aplicación de la tecnología al proceso diagnóstico y terapéutico en dermatología. Respecto a las técnicas de diagnóstico, realizamos una breve reseña sobre la tomografía de coherencia óptica, la microscopia láser multifotónica, la espectroscopia, la termografía y la resonancia magnética nuclear de 7 tesla, siendo que estas últimas también prometen incorporarse al arsenal diagnóstico en el futuro. En cuanto a los avances en terapéutica, la aplicación de tecnologías basadas en la luz, como el láser, ven ampliar sus aplicaciones con nuevas dianas y longitudes de onda, además de desarrollarse dispositivos de uso casero. Comentamos también el uso de plasma, ultrasonidos, radiofrecuencia, traser, fotoestimulación y administración transepidérmica de fármacos con fines terapéuticos. Finalmente, mencionamos los aspectos básicos de la nanotecnología y su proyección futura en el campo de la dermatología
We review novel technologies with diagnostic and therapeutic applications in dermatology. Among the diagnostic techniques that promise to become part of dermatologic practice in the future are optical coherence tomography, multiphoton laser scanning microscopy, Raman spectroscopy, thermography, and 7-T magnetic resonance imaging. Advances in therapy include novel light-based treatments, such as those applying lasers to new targets and in new wavelengths. Devices for home therapy are also appearing. We comment on the therapeutic uses of plasma, ultrasound, radiofrequency energy, total reflection amplification of spontaneous emission of radiation, light stimulation, and transepidermal drug delivery. Finally, we mention some basic developments in nanotechnology with prospects for future application in dermatology
Subject(s)
Humans , Dermatology/trends , Inventions , Diagnostic Imaging/methods , Biosensing Techniques , Dermatologic Agents/administration & dosage , Laser Therapy/methods , Nanotechnology/trends , Skin Diseases/diagnosis , Skin Diseases/therapyABSTRACT
We review novel technologies with diagnostic and therapeutic applications in dermatology. Among the diagnostic techniques that promise to become part of dermatologic practice in the future are optical coherence tomography, multiphoton laser scanning microscopy, Raman spectroscopy, thermography, and 7-T magnetic resonance imaging. Advances in therapy include novel light-based treatments, such as those applying lasers to new targets and in new wavelengths. Devices for home therapy are also appearing. We comment on the therapeutic uses of plasma, ultrasound, radiofrequency energy, total reflection amplification of spontaneous emission of radiation, light stimulation, and transepidermal drug delivery. Finally, we mention some basic developments in nanotechnology with prospects for future application in dermatology.
