1.
Clin Chem Lab Med
; 44(10): 1293-4, 2006.
Article
in English
| MEDLINE
| ID: mdl-17032145
Subject(s)
Immunoassay/methods , Myocardium/metabolism , Rheumatoid Factor/blood , Troponin I/blood , Adolescent , Adult , Aged , Aged, 80 and over , Biomarkers/blood , Child , False Positive Reactions , Female , Humans , Immunoassay/instrumentation , Immunoassay/statistics & numerical data , Immunologic Factors/blood , Male , Middle Aged
2.
Ann Clin Lab Sci
; 35(4): 453-4, 2005.
Article
in English
| MEDLINE
| ID: mdl-16254264
ABSTRACT
The aim of this study was to determine if sodium-citrate plasma is a suitable substitute for serum for cardiac troponin I (cTnI) measurement using the Beckman ACCESS 2 immunoassay. Linear regression analysis of cTnI levels in paired serum and sodium-citrate plasma samples from 80 patients provided a y-intercept of -0.0193 and a slope of 1.044. The correlation was good [r=0.995; 95% confidence interval 1.017 to 1.068, p <0.0001]. The paired results were not significantly different by Student's t-test. Serum and sodium-citrate plasma appear to be interchangeable as samples for cTnI measurement using the ACCESS 2 assay. Furthermore, the use of plasma reduces the turnaround time and may avoid false positive cTnI results due to residual fibrin.