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1.
Front Pediatr ; 9: 643387, 2021.
Article in English | MEDLINE | ID: mdl-33996689

ABSTRACT

Objective: This study aims to explore the occurrence of extrauterine growth retardation (EUGR) in preterm infants with a gestational age of <34 weeks, at discharge, and the factors influencing the occurrence of EUGR. Method: A retrospective analysis of 691 preterm infants with a gestational age of less than 34 weeks, born in our hospital over the past 3 years. At discharge, the growth indicators head circumference, weight, and length were used to divide the infants into an EUGR group (n = 255) and the non-EUGR group (n = 436). The occurrence of EUGR and its influencing factors were then analyzed. Results: Of the 691 preterm infants evaluated for inclusion in the study, 255 cases (36.9%) met the requirements of EUGR at discharge. The different growth indicators used, i.e., weight, length, and head circumference, classified the infants differently. The incidence of EUGR using these measures was 30.2% (209), 27.9% (193), and 23.2% (161), respectively. The results of a univariate analysis showed that gestational age, birth weight, intrauterine growth retardation (IUGR), maternal gestational hypertension, age at which the infant commenced feeding, duration of the application of an invasive ventilator, length of hospital stay, nosocomial infection, respiratory and gastrointestinal diseases, symptomatic patent ductus arteriosus, and the early onset of neonatal sepsis were correlated with the occurrence of EUGR. Further logistic multivariate regression analysis revealed that low gestational age, low birth weight, complicated IUGR, respiratory distress syndrome, and necrotizing enterocolitis were independent risk factors for EUGR in preterm infants with a gestational age <34 weeks. Conclusion: In preterm infants with a gestational age <34 weeks in our hospital, there is a high incidence of EUGR, which is affected by factors such as the gestational age, birth weight, IUGR, respiratory distress syndrome, necrotizing enterocolitis, and other factors.

2.
Clin Neuropharmacol ; 37(6): 190-1, 2014.
Article in English | MEDLINE | ID: mdl-25384077

ABSTRACT

Bruxism is an involuntary movement, including teeth grinding and clenching, which occur primarily during sleep. Although Behçet disease and posttraumatic stress disorder both have a high prevalence of sleep problems, bruxism is extremely rare in these 2 disorders. Here, we report a rare case of concurrent Behçet disease and posttraumatic stress disorder, which presented with antidepressant-refractory sleep disturbance accompanied by teeth grinding, clenching, and snoring that was successfully treated with gabapentin.


Subject(s)
Amines/therapeutic use , Behcet Syndrome/complications , Cyclohexanecarboxylic Acids/therapeutic use , Sleep Bruxism/complications , Sleep Bruxism/drug therapy , Stress Disorders, Post-Traumatic/complications , gamma-Aminobutyric Acid/therapeutic use , Adult , Gabapentin , Humans
3.
N Engl J Med ; 370(7): e11, 2014 Feb 13.
Article in English | MEDLINE | ID: mdl-24521132

ABSTRACT

A 48-year-old woman presented to the emergency department with severe otalgia of 1 day's duration. Bloody otorrhea in the left ear was noted after her hearing aid was removed. A video shows findings in the auditory canal.


Subject(s)
Ear Canal/pathology , Foreign Bodies/pathology , Animals , Drosophila , Female , Humans , Middle Aged
5.
Clin Neuropharmacol ; 32(4): 232-3, 2009.
Article in English | MEDLINE | ID: mdl-19644232

ABSTRACT

Somnambulism consists of variously complex behaviors that may result in harm to self or to others. Many different medications have been reported to induce somnambulism, and a few of them are newer antidepressants. A 40-year-old woman with history of major depression who experienced new onset somnambulism for successive 3 nights, whereas the antidepressant mirtazapine was increased from 30 to 45 mg/d. The notable and complex sleepwalking symptoms terminated dramatically on the first night after withdrawal of mirtazapine. There is clearly a cause-and-effect relationship between the treatment of higher-dosage mirtazapine and development of somnambulism. It might be related to the different affinities to 5-hydroxytryptamine 2 (5-HT(2)) and H(1) receptors at different dosages of mirtazapine, which explain the patient experiencing sleepwalking episodes exclusively at higher doses of mirtazapine. Clinical physicians should be aware of this adverse effect and taper or discontinue the regimen if sleepwalking develops.


Subject(s)
Antidepressive Agents, Tricyclic/adverse effects , Depressive Disorder, Major/drug therapy , Mianserin/analogs & derivatives , Somnambulism/chemically induced , Adult , Depressive Disorder, Major/complications , Depressive Disorder, Major/psychology , Dose-Response Relationship, Drug , Female , Humans , Mianserin/adverse effects , Mirtazapine , Somnambulism/psychology
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