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1.
Sci Total Environ ; 788: 147856, 2021 Sep 20.
Article in English | MEDLINE | ID: mdl-34134387

ABSTRACT

In order to meet the IMO Tier III emissions regulations and reduce environmental pollution, many ocean-going vessels have installed the marine SCR system to reduce NOx emissions. However, the investment cost and operation cost of the marine SCR system, as well as the factors affecting the SCR cost are still the problems that need to be studied. In this paper, MAN S46 diesel engine matched SCR system was taken as the research object, and a cost calculation model of Marine SCR system based on cost analysis method has been proposed. The relationship between SCR system cost and some factors such as unit capacity, unit running time and inlet NOx concentration have been analyzed. The research we have done suggests that operating time, NOx inlet concentration, and emission limits are the three main important factors in the operating cost of an SCR system. Among the various secondary costs of operating costs, the reducing agent cost, fuel increase cost, and indirect annual cost account for 60%, 24%, and 7%, respectively. Moreover, the results suggest that the unit denitration cost of the matched SCR system is highly affected by the power of the diesel engine and annual running time. This study demonstrated clearly the relationship between emission control and economic cost of SCR system for marine diesels and was expected to provide a theoretical basis for sustainable development in marine environmental protection policies.

2.
Environ Sci Pollut Res Int ; 27(12): 12851-12865, 2020 Apr.
Article in English | MEDLINE | ID: mdl-30734255

ABSTRACT

In order to avoid the production of sulfates and nitrates in marine diesel engines that burn sulfur-containing fuels, the operating temperature of their high-pressure selective catalytic reduction (HP-SCR) systems should be higher than 320 °C. For marine low-speed diesel engines, only the pre-turbine exhaust gas temperature can meet this requirement under specific conditions, with the main engine modulation method helping to increase the exhaust gas temperature. However, the main engine modulation method brings down the power output and fuel economy of the main engine and causes the matching problem of the turbine and the other devices with the main engine. The original engine model of the marine low-speed diesel engine and the high-pressure SCR system configuration model have been constructed using one-dimensional simulation software. In addition, the performance of the high-pressure SCR system under the conditions of low-sulfur and high-sulfur exhaust gas was thoroughly analyzed. Moreover, the two main engine modulation schemes of the scavenging bypass and the turbine exhaust bypass of the original engine matching with the high-pressure SCR system were studied. The study found that the weighted average value of the NOx under the condition of low-sulfur exhaust gas met with the requirement of the IMO Tier III regulations when the low-speed diesel engine was matched with the high-pressure SCR system. However, the weighted average value of the NOx under the condition of high-sulfur exhaust gas was slightly higher than that required by the IMO Tier III regulation. In addition, the optimal main engine modulation scheme for this low-speed diesel engine was clarified by comparing the effects of the scavenging bypass and the turbine exhaust bypass modulation on the exhaust performance, and the working performance of the original engine. With an opening of 0.4 of the CBV valve under 25% engine load, the weighted average NOx of the original exhaust gas was 3.38 g/(kW·h), the power had decreased by 0.7%, and the fuel consumption had increased by 1.0%. Furthermore, when the EGB valve opening was 0.3, the weighted average value of NOx was 3.31 g/(kW·h), the power had reduced by 2.4% and the fuel consumption had increased by 2.5%. Both modulation scheme methods made the exhaust performance of the original engine meet the requirements of the IMO Tier III emission regulations, but the scavenging bypass modulation scheme had less impact on the original engine's performance.


Subject(s)
Gasoline , Vehicle Emissions , Catalysis , Nitrogen Oxides/analysis , Sulfur
3.
Sci Total Environ ; 706: 135444, 2020 Mar 01.
Article in English | MEDLINE | ID: mdl-31862600

ABSTRACT

Exhaust gas recirculation (EGR) can be widely used to reduce the oxynitride (NOx) pollution in Low-Speed Two-Stroke Marine Diesel Engines. In this paper, two EGR systems (HP EGR1 and LP EGR2) were investigated in terms of the influence of different rates on the brake specific fuel consumption (BSFC) and the NOx emissions. As for this simulation, the exhaust gas cleaning water treatment was not concluded. Besides, Miller Cycle was used to determine the influence of its valve timing on BSFC and NOx emissions. The combination of Miller Cycle and HP EGR system decreased the NOx emissions, which could meet the IMO3 Tier III standard, 3.4 g/kWh. Moreover, the influence of the EGR cooling temperature was discussed. Finally, a fuzzy comprehensive evaluation model was developed to evaluate the two EGR systems. The results showed that when the HP EGR system and the LP EGR system were all operating at a maximum EGR rate, LP EGR system showed more advantages.

4.
Sci Rep ; 8(1): 7837, 2018 05 18.
Article in English | MEDLINE | ID: mdl-29777128

ABSTRACT

Deep vein thrombosis (DVT) and pulmonary embolism (PE) have high morbidity, reduce quality of life, and can cause death. Biomarkers or genetic risk factors have not been identified in patients with DVT. In present study, serum of 61 patients suffering from DVT and a rat DVT model (n = 10) were assayed by a proton nuclear magnetic resonance (1H NMR) metabolomics technique combing with multivariate statistical analysis to identify the metabolites. The MetPA platform was used to identify differences in the metabolic pathways between the rat model and patients. The metabolomics results discovered that 11 different metabolites in rats and 20 different metabolites in DVT patients. Seven metabolites both altered in the rats and patients. Moreover, we observed changes in the metabolic pathways, including carbohydrate metabolism, lipid metabolism, and amino acid metabolism that were induced immediately by the thrombosis. Pathway of aminoacyl-tRNA biosynthesis perturbed only in the patients which was associated with the genetic risk factor of DVT. The study demonstrated that serum 1H NMR metabolomics can be used to diagnose DVT in the clinic. The altered pathways related to thrombosis and genetics will provide a foundation and new strategies for understanding the pathological mechanism and pharmacological targets of DVT.


Subject(s)
Biomarkers/blood , Metabolomics/methods , Serum/chemistry , Venous Thrombosis/metabolism , Animals , Disease Models, Animal , Female , Humans , Male , Multivariate Analysis , Proton Magnetic Resonance Spectroscopy , ROC Curve , Rats , Venous Thrombosis/blood
5.
Behav Brain Res ; 317: 367-373, 2017 01 15.
Article in English | MEDLINE | ID: mdl-27713001

ABSTRACT

Levo-tetrahydropalmatine (l-THP) is an alkaloid purified from the Chinese herbs Corydalis and Stephania and has been used in many traditional Chinese herbal preparations for its sedative, analgesic and hypnotic properties. Previous studies demonstrated that l-THP has antagonistic activity on dopamine receptors; thus, it may have potential therapeutic effects on drug abuse. However, whether l-THP affects ketamine-induced conditioned place preference (CPP) remains unclear. Therefore, the present study was designed to evaluate the effects of l-THP on the rewarding behavior of ketamine through CPP. Results revealed that ketamine (5, 10 and 15mg/kg) induced CPP in rats. Furthermore, Ketamine (10mg/kg) promoted the phosphorylation of extracellular-regulated kinase (ERK) and cAMP responsive element binding protein (CREB) in the hippocampus (Hip) and caudate putamen (CPu), but not in the prefrontal cortex (PFc). l-THP (20mg/kg) co-administered with ketamine during conditioning inhibited the acquisition of ketamine-induced CPP in rats. Furthermore, l-THP (20mg/kg) prevented the enhanced phosphorylation of ERK and CREB in CPu and Hip. These results suggest that l-THP has potential therapeutic effects on ketamine-induced CPP. The underlying molecular mechanism may be related to its inhibitory effect on ERK and CREB phosphorylation in Hip and CPu. The present data supports the potential use of l-THP for the treatment of ketamine addiction.


Subject(s)
Antipsychotic Agents/pharmacology , Berberine Alkaloids/pharmacology , CREB-Binding Protein/metabolism , Conditioning, Operant/drug effects , Excitatory Amino Acid Antagonists/pharmacology , Hippocampus/metabolism , Ketamine/pharmacology , Mitogen-Activated Protein Kinase Kinases/metabolism , Animals , Dose-Response Relationship, Drug , Hippocampus/drug effects , Male , Phosphorylation/drug effects , Putamen/drug effects , Rats , Rats, Sprague-Dawley
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