Subject(s)
Cicatrix , Fetal Diseases/etiology , Gangrene/etiology , Uterine Perforation/complications , Adult , Constriction, Pathologic , Female , Gangrene/therapy , Humans , Infant, Newborn , Leg/pathology , PregnancySubject(s)
Colposcopy , Community Health Services , Uterine Cervical Diseases/diagnosis , Adult , Female , Humans , Middle Aged , Pilot Projects , United KingdomABSTRACT
Placentas of 84 antenatal patients have been examined throughout pregnancy (14-40 weeks of gestation). The coefficient of variation (the standard deviation divided by the mean) of echo-peak amplitude distributions obtained from placental images was used to characterize the placentas in different groups. Placentas of smokers yielded higher coefficient of variation values throughout pregnancy (P less than 0.05). This placental texture index was significantly lower for nonsmoking mothers of low-birth-weight babies after 30 weeks of gestation (P less than 0.001). Quantitative analysis of placental appearance may be of clinical value in selecting nonsmoking women at risk for low-birth-weight babies during the third trimester.
Subject(s)
Placenta , Ultrasonography , Female , Gestational Age , Humans , Infant, Low Birth Weight , Infant, Newborn , Infant, Small for Gestational Age , Placenta/pathology , Pre-Eclampsia/pathology , Pregnancy , SmokingABSTRACT
Uterine activity was measured quantitatively during subsequent labor after prostaglandin E2 gel (PGE2). Thirty primigravidae with a low Bishop score were included in this randomized double-blind study. Fewer women who received PGE2 required subsequent surgical induction. The pattern of uterine activity was different. Cervical dilatation was achieved with less uterine activity in the PGE2 group, especially during the shorter latent phase.
Subject(s)
Cervix Uteri/drug effects , Labor, Induced , Prostaglandins E/pharmacology , Uterine Contraction/drug effects , Adult , Clinical Trials as Topic , Dinoprostone , Double-Blind Method , Female , Humans , Parity , PregnancyABSTRACT
Analysis of the digitised ultrasonic images of in vivo placentae at 15-18 weeks gestation has revealed various textural differences. These have been correlated with smoking, visual appearance and the subsequent development of hypertension. The total number of patients included in this study was 98, of which 70 had images suitable for analysis. There were no significant textural differences between the images of the placentae of smokers and non-smokers nor did the spatially dependent co-occurrence matrices correlate with visual appearance. Textural differences were however detected when the placentae of the normotensive group were compared to those of patients who subsequently developed hypertension (latent hypertension) in the third trimester of pregnancy (p less than 0.05 Mann Whitney 'U' test).
Subject(s)
Hypertension/diagnosis , Placenta/anatomy & histology , Pregnancy Complications, Cardiovascular/diagnosis , Pregnancy Complications/diagnosis , Smoking , Ultrasonography , Female , Humans , Pre-Eclampsia/diagnosis , Pregnancy , Subtraction Technique , Time FactorsABSTRACT
The Hamou microcolpohysteroscope was used to measure the extension of cervical intraepithelial neoplasia into the endocervical canal in patients before cone biopsy of the cervix. These measurements showed good correlation with those found on subsequent histological assessment.
Subject(s)
Cervix Uteri/pathology , Uterine Cervical Neoplasms/pathology , Biopsy , Colposcopes , Female , Humans , Uterus/pathologyABSTRACT
Six further cases of acute fatty liver of pregnancy are presented and discussed in relation to the world literature on this rare disease of pregnancy, the aetiology of which is still unknown. The importance of vomiting in late pregnancy is emphasized. A common feature seems to be a metabolic stress, possibly related to infection, which tips a susceptible liver into metabolic failure.
