ABSTRACT
In the absence of heart failure or cardiogenic shock, cardiac involvement diagnosis in icteric leptospirosis is possible on the basis of abnormal electrocardiograms. As metabolic and electrolytic disorders are frequently seen during acute leptospirosis infection, they may be responsible for some electrocardiograms changes. We conducted a study to assess if creatine phosphokinase isoenzyme determinations are useful in selecting patients with a high cardiac involvement suspicion. Sixty-nine patients were studied prospectively. Ten patients out of 16 with cardiac involvement and 25 without had high CK-MB levels (p > 0.05), although mean values of abnormal CK-MB levels were higher in the group with cardiac involvement (p < 0.05). Our analysis indicates that serum CK-MB determination does not provide a specific indicator of myocardial involvement in the course of icteric leptospirosis.
Subject(s)
Creatine Kinase/blood , Heart Diseases/diagnosis , Heart Diseases/microbiology , Weil Disease/complications , Adult , Female , Heart Diseases/blood , Humans , Isoenzymes , Male , Prospective StudiesABSTRACT
Two male black patients, 18 and 12-year-old, with mental retardation and typical elfin face, presented with severe supravalvular aortic stenosis, thus characterizing Williams's or aortic supravalvular stenosis syndrome. Both were submitted to surgical treatment of the stenosis, and are asymptomatic after a one and four years follow-up. For the first time this syndrome, in its classical form, is described in black patients.
Subject(s)
Aortic Valve Stenosis/ethnology , Adolescent , Aortic Valve Stenosis/diagnosis , Aortic Valve Stenosis/physiopathology , Aortic Valve Stenosis/surgery , Aortography , Black People , Echocardiography , Electrocardiography , Heart Defects, Congenital , Hemodynamics , Humans , Male , Radionuclide VentriculographyABSTRACT
Foi estudada a correlacao existente entre a massa ventricular esquerda (MVE) determinada pela angiocardiografia e parametros eletrocardiograficos de hipertrofia ventricular esquerda (HVE) e tambem a possibilidade de dados do ECG diferenciarem normais de portadores de insuficiencia aortica (IA) e insuficiencia mitral ( IM ) cronicas. NO ECG estudou-se a QRS, deflexao intrinsecoide, duracao de QRS, ondas S de V1 e V2 e R de V5 e V6, maior amplitude de QRS nos planos horinzontal e frontal, a T, indices de Lewis, White-Block e Sokolow-Lyon e criterio de pontos de Romhilt.Foram estudados 75 pacientes. Grupo normal I (n=13) como controle angiografico, normal II (n=16) como controle eletrocardiografico, aorticos (n=33) e mitrais (n=13).Na IM nao se obteve correlacao entre MVE de ECG de HVE embora, os mesmos parametros diferenciassem o grupo normal II dos mitrais, exceto duracao do QRS, aT e maior amplitude do QRS em perfiericas. Na IA obteve-se correlacao entre a HVE e SV1, SV2 RV5, RV6, deflexao intrinsecoide, maior amplitude precordial, indice de SokolovLyon e escore de pontos de Romhilt. Todos os parametros estudados diferenciaram normais II de aorticos, exceto aT. Conclui-se pela correlacao significativa entre MVE e parametros de ECG na IA cronica e pela possibilidade de dados de ECG diferenciarem normais de portadores de IA e IM cronicas
