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Med Mal Infect ; 42(3): 119-25, 2012 Mar.
Article in French | MEDLINE | ID: mdl-22341665

ABSTRACT

OBJECTIVE: The authors retrospectively studied the epidemiological, clinical, diagnostic and therapeutic aspects of 71 cases of visceral leishmaniasis from 1998 to 2009. POPULATION AND METHODS: The diagnosis was made by finding Leishmania amastigotes in bone marrows smears and/or by serology. RESULTS: Most cases occur in winter (35.2%) and in spring (36.6%). The source areas are endemic ones located in the north of Algeria (74.6%) and more rarely arid or semi-arid climate areas (8.4%). 88.7% of patients are children. The sex ratio is 1.53. The clinical characteristics are: fever (77.4%), paleness (43.6%); splenomegaly (83%), hepatomegaly (57.7%). The biological anomalies are: anemia (56.3%), thrombocytopenia (33.8%), and leucopenia (28.1%). N-methylglucamine (Glucantime(®)) was most often prescribed (70.4%). Four deaths (5.6%) were recorded. CONCLUSION: Visceral leishmaniasis remains a pediatric affection but does not spare adults.


Subject(s)
Hospitals, University/statistics & numerical data , Leishmaniasis, Visceral/epidemiology , Adolescent , Adult , Age Distribution , Aged , Algeria/epidemiology , Animals , Antiprotozoal Agents/therapeutic use , Bone Marrow/parasitology , Child , Child, Preschool , Dog Diseases/epidemiology , Dog Diseases/parasitology , Dogs/parasitology , Endemic Diseases , Humans , Infant , Insect Vectors/parasitology , Leishmania infantum/isolation & purification , Leishmaniasis, Visceral/diagnosis , Leishmaniasis, Visceral/transmission , Leishmaniasis, Visceral/veterinary , Middle Aged , Phlebotomus/parasitology , Retrospective Studies , Sex Distribution , Young Adult , Zoonoses
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