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2.
An. pediatr. (2003, Ed. impr.) ; 75(3): 204-204[e1-e11], sept. 2011. tab, ilus
Article in Spanish | IBECS | ID: ibc-94271

ABSTRACT

Con la denominación de talla baja idiopática (TBI) se agrupan una serie de entidades clínicas de etiología desconocida que tienen en común un retraso crónico de crecimiento con talla inferior a −2 desviaciones estándar (DE), con preservación de la armonía entre los segmentos corporales y en las que, en su evolución espontánea, las expectativas de talla adulta son inferiores a −2 DE. Es un diagnóstico de exclusión que exige una evaluación clínica, bioquímica, hormonal y molecular minuciosa con el objetivo de descartar cualquier etiología conocida del retraso de crecimiento, especialmente el retraso constitucional del crecimiento y desarrollo (RCCD). La TBI es un diagnóstico frecuente entre los pacientes que consultan por retraso de crecimiento, existiendo lagunas y controversias sobre su abordaje diagnóstico y terapéutico. Este documento de consenso recoge información actualizada sobre la definición, diagnóstico y tratamiento de la TBI, y aporta datos y recomendaciones que no han sido contemplados en documentos anteriores (AU)


Idiopathic short stature (ISS) refers to all clinical conditions involving an alteration of growth (height <−2 SD) of unknown cause, with preservation of proportionality among body segments, with the expectation of adult height < −2 SDS, and in which a diagnosis of constitutional delay of growth and development has been previously ruled out. ISS is an exclusion diagnostic which requires clinical, biochemical, hormonal and molecular studies in order to rule out all known causes of growth retardation and short stature.ISS is a frequent diagnosis among children with short stature. Despite its frequency, there is still controversy on the best diagnostic and therapeutic approach when treating patients with ISS. This consensus document contains updated information on the definition, diagnosis and treatment of ISS, and provides new data and recommendations that have not been addressed in previous documents (AU)


Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Child , Adolescent , Failure to Thrive/classification , Failure to Thrive/diagnosis , Failure to Thrive/drug therapy , Growth Hormone , Growth Hormone/therapeutic use , Anabolic Agents/therapeutic use , Aromatase Inhibitors/therapeutic use , Gonadotropin-Releasing Hormone/analogs & derivatives , Insulin-Like Growth Factor I/analogs & derivatives , Failure to Thrive/epidemiology , Failure to Thrive/etiology , Growth Hormone/physiology
3.
An Pediatr (Barc) ; 75(3): 204.e1-11, 2011 Sep.
Article in Spanish | MEDLINE | ID: mdl-21723798

ABSTRACT

Idiopathic short stature (ISS) refers to all clinical conditions involving an alteration of growth (height<-2 SD) of unknown cause, with preservation of proportionality among body segments, with the expectation of adult height < -2 SDS, and in which a diagnosis of constitutional delay of growth and development has been previously ruled out. ISS is an exclusion diagnostic which requires clinical, biochemical, hormonal and molecular studies in order to rule out all known causes of growth retardation and short stature. ISS is a frequent diagnosis among children with short stature. Despite its frequency, there is still controversy on the best diagnostic and therapeutic approach when treating patients with ISS. This consensus document contains updated information on the definition, diagnosis and treatment of ISS, and provides new data and recommendations that have not been addressed in previous documents.


Subject(s)
Growth Disorders/diagnosis , Growth Disorders/drug therapy , Algorithms , Child , Humans
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