ABSTRACT
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Subject(s)
Humans , Female , Middle Aged , Immunoglobulin G/immunology , Inflammation/complications , Inflammation/immunology , Orbital Diseases/complications , Orbital Diseases/immunology , Orbital Pseudotumor/etiology , Immunoglobulin G4-Related Disease/diagnosis , Exophthalmos/diagnostic imagingSubject(s)
Immunoglobulin G , Orbital Pseudotumor/immunology , Female , Humans , Middle Aged , Orbital Pseudotumor/diagnosisABSTRACT
Presentamos el caso de un varón institucionalizado de 57 años, afectado por síndrome de Down, que presentó lesiones purpúricas en manos y extremidades inferiores tras administración de una dosis de amoxicilina-ácido clavulánico. Se sospechó una reacción de hipersensibilidad por fármacos, pero la reacción cutánea persistió tras la suspensión del antibiótico. Tras descartar otras etiologías, fue diagnosticado de escorbuto. El paciente fue tratado con suplementos de vitamina C, mostrando clara mejoría de las lesiones. El escorbuto no es un diagnóstico frecuente en la actualidad, sin embargo esta patología de otras épocas no ha desaparecido del todo. Se trata de una enfermedad que resulta fácil olvidar al plantearnos un diagnóstico diferencial y cuyo tratamiento con la suplementación vitamínica es simple y efectivo (AU)
We report the case of an institutionalized 57-year-old man affected by Down syndrome, with purpura in hands and lower extremities after the administration of a dose of amoxicillin-clavulanic acid. We suspected a drug hypersensitivity reaction but the skin reaction persisted after discontinuation of the antibiotic. After ruling out any other etiology, scurvy was diagnosed. The patient was treated with vitamin C supplements, showing a clear improvement. Scurvy is not a common diagnosis at the present time, but this disease from the past has not disappeared entirely. It can be easily overlooked in differential diagnosis, but vitamin supplementation is a simple and effective treatment (AU)
Subject(s)
Humans , Male , Middle Aged , Purpura/diagnosis , Purpura/drug therapy , Drug Hypersensitivity/drug therapy , Amoxicillin-Potassium Clavulanate Combination/therapeutic use , Exanthema/drug therapy , Ascorbic Acid/therapeutic use , Lower Extremity/injuries , Scurvy/complications , Exanthema/complications , Scurvy/drug therapy , Diagnosis, Differential , Down Syndrome/complicationsABSTRACT
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Subject(s)
Humans , Male , Adult , Self Administration/methods , Self Administration/standards , Self Administration , Insulin/therapeutic use , Hypoglycemia/diagnosis , Hypoglycemia/therapy , Glucose/therapeutic use , Drug-Related Side Effects and Adverse Reactions/complications , Drug-Related Side Effects and Adverse Reactions/drug therapy , Doping in Sports/methods , Sports/standards , Sweating , Carbohydrates/therapeutic use , Family Practice/methods , Family Practice/standardsABSTRACT
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Subject(s)
Humans , Female , Aged , Keratoderma, Palmoplantar, Diffuse/congenital , Keratoderma, Palmoplantar, Diffuse/diagnosis , Keratoderma, Palmoplantar, Diffuse/prevention & control , Keratolytic Agents/pharmacology , Keratolytic Agents/therapeutic use , Retinoids/pharmacology , Retinoids/therapeutic use , Anti-Bacterial Agents/pharmacology , Anti-Bacterial Agents/therapeutic use , Antifungal Agents/pharmacology , Antifungal Agents/therapeutic useABSTRACT
OBJECTIVE: To report two new cases of IgG4-related retroperitoneal fibrosis, a recently described pathology. METHODS: We analyze two cases diagnosed in our center and performed a literature review. RESULT: IgG4 related disease is a recently described entity that includes previously not related pathologies. The clinical manifestations are highly variable and its presentation is usually subacute. The treatment of choice is glucocorticoids. In our first case the outcome was favorable with corticosteroids and azathioprine. However, the second case required surgery on 2 occasions with radical nephrectomy. The diagnosis of the latter was made nine years after the onset of symptoms when the biopsy was reviewed; at that moment immunosuppressive therapy was not started. CONCLUSIONS: It is very important to know and diagnose this disease because of the good response to treatment that prevents complications.
Subject(s)
Immunoglobulin G , Retroperitoneal Fibrosis/immunology , Adult , Aged , Female , Humans , Male , Retroperitoneal Fibrosis/diagnosis , Retroperitoneal Fibrosis/therapyABSTRACT
Los trastornos de la conducción son un fenómeno poco frecuente de la endocarditis infecciosa y se asocia a un aumento de la mortalidad. Presentamos el caso de un paciente con bloqueo cardiaco completo como debut de una endocarditis infecciosa...
Conduction abnormalities are a rare phenomenon in Infective Endocarditis; and they are usually associated with an increase in mortality. We present the case of a patient with complete heart block as the debut of Infective Endocarditis...
Subject(s)
Humans , Male , Aged , Heart Block , Endocarditis , FeverABSTRACT
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