ABSTRACT
Authors present a case of Maestre de San Juan-Kallman syndrome in a male 14 year old, with hypogonadotrophic hypogonadism and anosmia, and with other associated malformations (cryptorchism, epilepsy, hypoacusia and chromosomal anomalies). Standard values of FSH and LH are undetectable. After stimulation with LH-RH, a continued release of gonadotropins is produced. With the clomiphene stimulation there is a negative response.
Subject(s)
Abnormalities, Multiple/blood , Gonadotropins, Pituitary/deficiency , Hypogonadism/blood , Olfaction Disorders/blood , Adolescent , Chromosome Aberrations , Clomiphene , Cryptorchidism/blood , Epilepsy/blood , Gonadotropin-Releasing Hormone , Humans , Male , SyndromeABSTRACT
It has been done an analysis of a case of eccrine porome, based on the morphology, considering the actual tecnical publications on the matter. The morphogenesis of the formation of this nevoid tumor is established by the continuity between the main body of the tumor and the underneath eccrine sweat glands. These glands present signs of hyperplasia, which in the highest levels present destructuration of the excretory duct and morphological modifications of the cells which are conditioned by the functional adaptation at different levels. In this way there is proliferation of structures, similar to the different parts of syringuium and acrosyringuium producing this hamartomatous neoformation.